SENP1 Antikörper (Middle Region)

Produktnummer ABIN2786045

Produktdetails anti-SENP1 Antikörper

Target: SENP1 (SUMO1/sentrin Specific Peptidase 1 (SENP1))

Bindungsspezifität: Middle Region

Reaktivität: Human, Maus, Ratte, Hund, Rind (Kuh), Pferd, Kaninchen, Meerschweinchen, Zebrafisch (Danio rerio)

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser SENP1 Antikörper ist unkonjugiert

Applikation: Western Blotting (WB)

Sequenz: PQQMNGSDCG MFACKYADCI TKDRPINFTQ QHMPYFRKRM VWEILHRKLL

Homologie: Cow: 100%, Dog: 100%, Guinea Pig: 100%, Horse: 100%, Human: 100%, Mouse: 100%, Rabbit: 100%, Rat: 100%, Zebrafish: 77%

Produktmerkmale: This is a rabbit polyclonal antibody against SENP1. It was validated on Western Blot using a cell lysate as a positive control.

Aufreinigung: Affinity Purified

Immunogen: The immunogen is a synthetic peptide directed towards the middle region of human SENP1

Anwendungsinformationen

Applikationshinweise: Optimal working dilutions should be determined experimentally by the investigator.

Kommentare:

Antigen size: 643 AA

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Konzentration: Lot specific

Buffer: Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handhabung: Avoid repeated freeze-thaw cycles.

Lagerung: -20 °C

Informationen zur Lagerung: For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.

Details zu SENP1

Target: SENP1 (SUMO1/sentrin Specific Peptidase 1 (SENP1))

Andere Bezeichnung: SENP1 (SENP1 Produkte)

Synonyme: SuPr-2 antikoerper, 2310046A20Rik antikoerper, D15Ertd528e antikoerper, E330036L07Rik antikoerper, suPr-2 antikoerper, senp1 antikoerper, senp1a antikoerper, xsenp1 antikoerper, SENP1 antikoerper, Senp1 antikoerper, senp1b antikoerper, SUMO1/sentrin specific peptidase 1 antikoerper, SUMO1/sentrin specific peptidase 1 S homeolog antikoerper, sentrin/SUMO-specific protease 1 antikoerper, SUMO1/sentrin specific peptidase 1 L homeolog antikoerper, SENP1 antikoerper, Senp1 antikoerper, senp1.S antikoerper, senp1.L antikoerper, senp1 antikoerper

Hintergrund: The covalent modification of proteins by the small ubiquitin-like protein SUMO is implicated in the regulation of nucleocytoplasmic transport, genomic stability, gene transcription, and other processes. Sumoylation is catalyzed on target lysine residues by a multienzyme process and is reversed by desumoylating enzymes such as SENP1.
Alias Symbols: SuPr-2
Protein Interaction Partner: USP25, RABGAP1, SUMO1, TP53, SP100, SUMO2, SUMO3, RANGAP1, PRDM1, BAG3, LMNA, APP, UBD, U90, HIPK2, ISG15, RANBP2, HDAC2, ELAVL1, UBC, GCM1, RUVBL2, HDAC1, PARP1, HDAC4, KCNK1, SENP1, SP3,
Protein Size: 643

Molekulargewicht: 73 kDa

Gen-ID: 29843

NCBI Accession: NM_014554, NP_055369

Pathways: Positive Regulation of Endopeptidase Activity