TMOD3 Antikörper (Middle Region)
Kurzübersicht für TMOD3 Antikörper (Middle Region) (ABIN2786043)
Target
Alle TMOD3 Antikörper anzeigenReaktivität
Wirt
Klonalität
Konjugat
Applikation
-
-
Bindungsspezifität
- Middle Region
-
Verwendungszweck
- TMOD3 Antibody - middle region
-
Sequenz
- ITNTKFCNIM GSSNGVDQEH FSNVVKGEKI LPVFDEPPNP TNVEESLKRT
-
Homologie
- Cow: 100%, Dog: 100%, Guinea Pig: 93%, Horse: 93%, Human: 100%, Mouse: 100%, Rabbit: 100%, Rat: 100%, Zebrafish: 86%
-
Produktmerkmale
- This is a rabbit polyclonal antibody against TMOD3. It was validated on Western Blot using a cell lysate as a positive control.
-
Aufreinigung
- Affinity Purified
-
Immunogen
- The immunogen is a synthetic peptide directed towards the middle region of human TMOD3
-
-
-
-
Applikationshinweise
- Optimal working dilution should be determined by the investigator.
-
Kommentare
-
We also sell a specific blocking peptide that can be used in combination with this antibody. You can find the blocking peptide under AAP55078-100UG
-
Beschränkungen
- Nur für Forschungszwecke einsetzbar
-
-
-
Format
- Liquid
-
Konzentration
- 0.5 mg/mL
-
Buffer
- Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.
-
Konservierungsmittel
- Sodium azide
-
Vorsichtsmaßnahmen
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
-
Handhabung
- prevent freeze-thaw cycles
-
Lagerung
- 4 °C,-20 °C
-
Informationen zur Lagerung
- For short term use, store at 2-8C up to 1 week. For long term storage, store at -20 °C in small aliquots to prevent freeze-thaw cycles.
-
-
- TMOD3 (Tropomodulin 3 (TMOD3))
-
Andere Bezeichnung
- TMOD3
-
Hintergrund
-
Background Information: TMOD3 belongs to the tropomodulin family. It blocks the elongation and depolymerization of the actin filaments at the pointed end. The Tmod/TM complex contributes to the formation of the short actin protofilament, which in turn defines the geometry of the membrane skeleton. This gene is a necessary element in receptor tyrosine kinase pathways, possibly as a tyrosine phosphorylation target. It is involved in regulation of RAF in the MAPK pathway and may also play a role in a MAPK-independent pathway.
Gene Name: Tropomodulin 3 (ubiquitous)
Alternative Symbols: UTMOD
Protein Name: Tropomodulin-3
-
Molekulargewicht
- 39kDa
-
Gen-ID
- 29766
-
NCBI Accession
- NP_055362
-
UniProt
- Q9NYL9
-
Pathways
- Regulation of Actin Filament Polymerization
Target
-