TMOD3 Antikörper (Middle Region)

Produktnummer ABIN2786043

Der Kaninchen Polyklonal Anti-TMOD3-Antikörper wurde für WB validiert. Er ist geeignet, TMOD3 in Proben von Human, Maus, Ratte, Rind (Kuh), Hund, Kaninchen, Pferd, Meerschweinchen und Zebrafisch (Danio rerio) zu detektieren.

Kurzübersicht für TMOD3 Antikörper (Middle Region) (ABIN2786043)

Target: TMOD3 (Tropomodulin 3 (TMOD3))

Reaktivität: Human, Maus, Ratte, Rind (Kuh), Hund, Kaninchen, Pferd, Meerschweinchen, Zebrafisch (Danio rerio)

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser TMOD3 Antikörper ist unkonjugiert

Applikation: Western Blotting (WB)

Produktdetails anti-TMOD3 Antikörper

Bindungsspezifität: Middle Region

Sequenz: ITNTKFCNIM GSSNGVDQEH FSNVVKGEKI LPVFDEPPNP TNVEESLKRT

Homologie: Cow: 100%, Dog: 100%, Guinea Pig: 93%, Horse: 93%, Human: 100%, Mouse: 100%, Rabbit: 100%, Rat: 100%, Zebrafish: 86%

Produktmerkmale: This is a rabbit polyclonal antibody against TMOD3. It was validated on Western Blot using a cell lysate as a positive control.

Aufreinigung: Affinity Purified

Immunogen: The immunogen is a synthetic peptide directed towards the middle region of human TMOD3

Anwendungsinformationen

Applikationshinweise: Optimal working dilutions should be determined experimentally by the investigator.

Kommentare:

Antigen size: 352 AA

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Konzentration: Lot specific

Buffer: Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handhabung: Avoid repeated freeze-thaw cycles.

Lagerung: -20 °C

Informationen zur Lagerung: For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.

Details zu TMOD3

Target: TMOD3 (Tropomodulin 3 (TMOD3))

Andere Bezeichnung: TMOD3

Hintergrund: TMOD3 belongs to the tropomodulin family. It blocks the elongation and depolymerization of the actin filaments at the pointed end. The Tmod/TM complex contributes to the formation of the short actin protofilament, which in turn defines the geometry of the membrane skeleton. This gene is a necessary element in receptor tyrosine kinase pathways, possibly as a tyrosine phosphorylation target. It is involved in regulation of RAF in the MAPK pathway and may also play a role in a MAPK-independent pathway.
Alias Symbols: UTMOD
Protein Interaction Partner: UBC, PABPC1, YWHAE, PSMD9, PPP1CA, DHX15, PAN2, CSNK2A1, HNRNPUL2, PPIL3, AHCYL1, SULT1A1, PSMC4, PSMB7, NPC1, ATP6V1B1, LRRK2, FBXO25, ISG15, ARRB2, ARRB1, ELAVL1, SUMO2, DUSP23, TNFSF11, MAP1LC3B, Poc1b, Tubgcp3, Sass6, Trim69, Stag2, Pafah1b1, Erh, Cdk
Protein Size: 352

Molekulargewicht: 39 kDa

Gen-ID: 29766

NCBI Accession: NM_014547, NP_055362

UniProt: Q9NYL9

Pathways: Regulation of Actin Filament Polymerization