RABGEF1 Antikörper (N-Term)
Kurzübersicht für RABGEF1 Antikörper (N-Term) (ABIN2786039)
Target
Alle RABGEF1 Antikörper anzeigenReaktivität
Wirt
Klonalität
Konjugat
Applikation
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Bindungsspezifität
- N-Term
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Sequenz
- MSLKSERRGI HVDQSDLLCK KGCGYYGNPA WQGFCSKCWR EEYHKARQKQ
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Homologie
- Cow: 100%, Dog: 100%, Goat: 100%, Guinea Pig: 100%, Horse: 100%, Human: 100%, Mouse: 100%, Rabbit: 100%, Rat: 100%, Zebrafish: 86%
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Produktmerkmale
- This is a rabbit polyclonal antibody against RABGEF1. It was validated on Western Blot using a cell lysate as a positive control.
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Aufreinigung
- Affinity Purified
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Immunogen
- The immunogen is a synthetic peptide directed towards the N terminal region of human RABGEF1
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Applikationshinweise
- Optimal working dilutions should be determined experimentally by the investigator.
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Kommentare
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Antigen size: 491 AA
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Beschränkungen
- Nur für Forschungszwecke einsetzbar
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Format
- Liquid
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Konzentration
- Lot specific
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Buffer
- Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.
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Konservierungsmittel
- Sodium azide
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Vorsichtsmaßnahmen
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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Handhabung
- Avoid repeated freeze-thaw cycles.
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Lagerung
- -20 °C
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Informationen zur Lagerung
- For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.
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- RABGEF1 (RAB Guanine Nucleotide Exchange Factor (GEF) 1 (RABGEF1))
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Andere Bezeichnung
- RABGEF1
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Hintergrund
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RABGEF1 forms a complex with rabaptin-5 (RABPT5, MIM 603616) that is required for endocytic membrane fusion, and it serves as a specific guanine nucleotide exchange factor (GEF) for RAB5 (RAB5A, MIM 179512) (Horiuchi et al., 1997 [PubMed 9323142]).
Alias Symbols: FLJ32302, RABEX5, rabex-5
Protein Interaction Partner: TRIM15, CIPC, ZC2HC1C, TRIM54, RABGEF1, BLOC1S6, TXN2, THOC1, DAZAP2, UBC, TEAD4, RABEP1, DGCR6, TNKS1BP1, ROCK2, SLMAP, MON1A, RNF11, MON1B, RAB21, UBE2D3, UBE2D1, RAB5A, L1CAM, EEA1, ESR1, EGFR, RAB22A, GGA1, MAPK1, HRAS, YWHAG, YWHAB, KXD1, GGA2, RNF16
Protein Size: 491 -
Molekulargewicht
- 57 kDa
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Gen-ID
- 27342
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NCBI Accession
- NM_014504, NP_055319
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UniProt
- A8K3R3
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Pathways
- Regulation of Leukocyte Mediated Immunity, Positive Regulation of Immune Effector Process
Target
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