EDC4 Antikörper (N-Term)

Produktnummer ABIN2786009

Produktdetails anti-EDC4 Antikörper

Target: EDC4 (Enhancer of mRNA Decapping 4 (EDC4))

Bindungsspezifität: N-Term

Reaktivität: Human, Maus, Ratte, Hund, Meerschweinchen, Pferd, Kaninchen, Rind (Kuh), Zebrafisch (Danio rerio)

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser EDC4 Antikörper ist unkonjugiert

Applikation: Western Blotting (WB)

Sequenz: LQEKQVICLS GDDSSTCIGI LAKEVEIVAS SDSSISSKAR GSNKVKIQPV

Homologie: Cow: 100%, Dog: 100%, Guinea Pig: 100%, Horse: 100%, Human: 100%, Mouse: 100%, Rabbit: 100%, Rat: 100%, Zebrafish: 92%

Produktmerkmale: This is a rabbit polyclonal antibody against EDC4. It was validated on Western Blot using a cell lysate as a positive control.

Aufreinigung: Affinity Purified

Immunogen: The immunogen is a synthetic peptide directed towards the N terminal region of human EDC4

Anwendungsinformationen

Applikationshinweise: Optimal working dilutions should be determined experimentally by the investigator.

Kommentare:

Antigen size: 1401 AA

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Konzentration: Lot specific

Buffer: Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handhabung: Avoid repeated freeze-thaw cycles.

Lagerung: -20 °C

Informationen zur Lagerung: For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.

Referenzen für anti-EDC4 Antikörper (ABIN2786009)

Wang, Xu, Li, Li: "Synthesis, characterization, and antitumoral activity of polyoxometalate loaded starch nanocomplexes." in: Journal of nanoscience and nanotechnology, Vol. 5, Issue 6, pp. 905-8, (2005) (PubMed).

Details zu EDC4

Target: EDC4 (Enhancer of mRNA Decapping 4 (EDC4))

Andere Bezeichnung: EDC4 (EDC4 Produkte)

Synonyme: VARICOSE antikoerper, ge-1 antikoerper, hedls antikoerper, rcd-8 antikoerper, GE1 antikoerper, Ge-1 antikoerper, HEDL5 antikoerper, HEDLS antikoerper, RCD-8 antikoerper, RCD8 antikoerper, BC022641 antikoerper, si:ch211-237c7.1 antikoerper, wu:fe26b05 antikoerper, LRRG00115 antikoerper, Nrn1l antikoerper, RGD1309136 antikoerper, enhancer of mRNA decapping 4 antikoerper, Transducin/WD40 repeat-like superfamily protein antikoerper, enhancer of mRNA decapping 4 L homeolog antikoerper, EDC4 antikoerper, VCS antikoerper, edc4 antikoerper, Edc4 antikoerper, edc4.L antikoerper

Hintergrund: In the process of mRNA degradation, EDC4 seems to play a role in mRNA decapping. It is the component of a complex containing DCP2 and DCP1A which functions in decapping of ARE-containing mRNAs. EDC4 promotes complex formation between DCP1A and DCP2.It enhances the catalytic activity of DCP2 (in vitro).
Alias Symbols: Ge-1, HEDLS, RCD-8
Protein Interaction Partner: MDM2, DCP1B, DCP1A, UBC, DCP2, LGR4, WWOX, RPA3, RPA2, RPA1, BMI1, DIMT1, NELFB, IGF2BP3, G3BP1, EIF2B2, EIF2B3, RFC4, NMT1, ILF2, FKBP3, DDX1, ABCF1, ZFP36, YTHDC1, EDC3, vpu, GIT2, FBLN1, CCL5, UPF1, CRK, SIRT7, EIF2AK2, Edc4, Pds5a, tat,
Protein Size: 1401

Molekulargewicht: 152 kDa

Gen-ID: 23644

NCBI Accession: NM_014329, NP_055144

UniProt: Q6P2E9