EDC4 Antikörper (N-Term)

Produktnummer ABIN2786009

Es gibt 1 Publikation für dieses Produkt. Der Kaninchen Polyklonal anti-EDC4 Antikörper wird verwendet zum Nachweis von EDC4 in Proben von Human, Maus, Ratte, Hund, Meerschweinchen, Pferd, Kaninchen, Rind (Kuh) und Zebrafisch (Danio rerio). Er wurde validiert für WB.

Kurzübersicht für EDC4 Antikörper (N-Term) (ABIN2786009)

Target: EDC4 (Enhancer of mRNA Decapping 4 (EDC4))

Reaktivität: Human, Maus, Ratte, Hund, Meerschweinchen, Pferd, Kaninchen, Rind (Kuh), Zebrafisch (Danio rerio)

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser EDC4 Antikörper ist unkonjugiert

Applikation: Western Blotting (WB)

Produktdetails anti-EDC4 Antikörper

Bindungsspezifität: N-Term

Sequenz: LQEKQVICLS GDDSSTCIGI LAKEVEIVAS SDSSISSKAR GSNKVKIQPV

Homologie: Cow: 100%, Dog: 100%, Guinea Pig: 100%, Horse: 100%, Human: 100%, Mouse: 100%, Rabbit: 100%, Rat: 100%, Zebrafish: 92%

Produktmerkmale: This is a rabbit polyclonal antibody against EDC4. It was validated on Western Blot using a cell lysate as a positive control.

Aufreinigung: Affinity Purified

Immunogen: The immunogen is a synthetic peptide directed towards the N terminal region of human EDC4

Anwendungsinformationen

Applikationshinweise: Optimal working dilutions should be determined experimentally by the investigator.

Kommentare:

Antigen size: 1401 AA

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Konzentration: Lot specific

Buffer: Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handhabung: Avoid repeated freeze-thaw cycles.

Lagerung: -20 °C

Informationen zur Lagerung: For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.

Referenzen für anti-EDC4 Antikörper (ABIN2786009)

Wang, Xu, Li, Li: "Synthesis, characterization, and antitumoral activity of polyoxometalate loaded starch nanocomplexes." in: Journal of nanoscience and nanotechnology, Vol. 5, Issue 6, pp. 905-8, (2005) (PubMed).

Details zu EDC4

Target: EDC4 (Enhancer of mRNA Decapping 4 (EDC4))

Andere Bezeichnung: EDC4

Hintergrund: In the process of mRNA degradation, EDC4 seems to play a role in mRNA decapping. It is the component of a complex containing DCP2 and DCP1A which functions in decapping of ARE-containing mRNAs. EDC4 promotes complex formation between DCP1A and DCP2.It enhances the catalytic activity of DCP2 (in vitro).
Alias Symbols: Ge-1, HEDLS, RCD-8
Protein Interaction Partner: MDM2, DCP1B, DCP1A, UBC, DCP2, LGR4, WWOX, RPA3, RPA2, RPA1, BMI1, DIMT1, NELFB, IGF2BP3, G3BP1, EIF2B2, EIF2B3, RFC4, NMT1, ILF2, FKBP3, DDX1, ABCF1, ZFP36, YTHDC1, EDC3, vpu, GIT2, FBLN1, CCL5, UPF1, CRK, SIRT7, EIF2AK2, Edc4, Pds5a, tat,
Protein Size: 1401

Molekulargewicht: 152 kDa

Gen-ID: 23644

NCBI Accession: NM_014329, NP_055144

UniProt: Q6P2E9