NOMO1 Antikörper (NODAL Modulator 1) (C-Term)

Details for Product anti-NOMO1 Antibody No. ABIN2785997, Anbieter: Anmelden zum Anzeigen
Antigen
  • Nomo
  • PM5
  • D7Ertd156e
  • pM5
  • RGD1305240
  • NOMO2
  • DKFZP459L1733
  • Nomo1
  • NODAL modulator 1
  • nodal modulator 1
  • NOMO1
  • Nomo1
  • LOC515570
  • LOC714226
  • LOC100025365
  • LOC100174326
  • LOC100408200
  • LOC100464689
  • LOC100544619
  • LOC100626015
  • LOC454345
  • LOC489992
  • LOC100713781
Epitop
C-Term
19
18
14
6
4
3
2
2
1
Reaktivität
Rind (Kuh), Hund, Meerschweinchen, Pferd, Human, Maus, Kaninchen, Ratte (Rattus), Zebrafisch (Danio rerio)
95
30
28
3
3
2
2
1
1
Wirt
Kaninchen
93
2
Klonalität
Polyklonal
Konjugat
Dieser NOMO1 Antikörper ist unkonjugiert
8
8
8
7
6
6
1
1
1
1
1
1
1
1
1
1
1
Applikation
Immunohistochemistry (IHC), Western Blotting (WB)
51
41
27
18
13
5
3
2
2
1
1
1
Optionen
Hersteller
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Hersteller Produkt- Nr.
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Immunogen The immunogen is a synthetic peptide directed towards the C terminal region of human NOMO1
Blocking Peptide Zu diesem Produkt passt das Blocking Peptide ABIN980799.
Sequenz QDIAQGSYIA LPLTLLVLLA GYNHDKLIPL LLQLTSRLQG VRALGQAASD
Homologie Cow: 100%, Dog: 100%, Guinea Pig: 100%, Horse: 93%, Human: 100%, Mouse: 100%, Rabbit: 100%, Rat: 100%, Zebrafish: 86%
Produktmerkmale This is a rabbit polyclonal antibody against NOMO1. It was validated on Western Blot using a cell lysate as a positive control.
Reinigung Affinity Purified
Plasmids, Primers & others Plasmide, Primers & weitere NOMO1 products on genomics-online (e.g. as negative or positive controls)
Andere Bezeichnung NOMO1 (NOMO1 Antibody Abstract)
Hintergrund NOMO1 was originally thought to be related to the collagenase gene family. This gene is one of three highly similar genes in a region of duplication located on the p arm of chromosome 16. These three genes encode closely related proteins that may have the same function. The protein encoded by one of these genes has been identified as part of a protein complex that participates in the Nodal signaling pathway during vertebrate development. Mutations in ABCC6, which is located nearby, rather than mutations in this gene are associated with pseudoxanthoma elasticum (PXE). This gene encodes a protein originally thought to be related to the collagenase gene family. This gene is one of three highly similar genes in a region of duplication located on the p arm of chromosome 16. These three genes encode closely related proteins that may have the same function. The protein encoded by one of these genes has been identified as part of a protein complex that participates in the Nodal signaling pathway during vertebrate development. Mutations in ABCC6, which is located nearby, rather than mutations in this gene are associated with pseudoxanthoma elasticum (PXE).
Alias Symbols: Nomo, PM5, NOMO3
Protein Interaction Partner: UBC, TRIM63, TRIM55, EXOSC10, FBXO6, UPF2, STAT1, ECT2, TIMM10, PLEC, ILF3, UBQLN4, SHBG, CDK2, TOM1L1, BAG6, NCLN,
Protein Size: 1222
Molekulargewicht 134 kDa
Gen-ID 23420
NCBI Accession NM_014287, NP_055102
UniProt P69849
Applikations-hinweise Optimal working dilutions should be determined experimentally by the investigator.
Kommentare

Antigen size: 1222 AA

Beschränkungen Nur für Forschungszwecke einsetzbar
Format Liquid
Konzentration Lot specific
Buffer Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.
Konservierungs-mittel Sodium azide
Vorsichtsmaßnahmen This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
Handhabung Avoid repeated freeze-thaw cycles.
Lagerung -20 °C
Informationen zur Lagerung For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.
Bilder des Herstellers
Immunohistochemistry (IHC) image for anti-NODAL Modulator 1 (NOMO1) (C-Term) antibody (ABIN2785997) NOMO1 antibody - C-terminal region (ARP54998_P050) Catalog Number: ARP54998_P050 For...
Western Blotting (WB) image for anti-NODAL Modulator 1 (NOMO1) (C-Term) antibody (ABIN2785997) WB Suggested Anti-NOMO1 Antibody Titration: 0.2-1 ug/ml ELISA Titer: 1:312500 Positiv...
Allgemeine Veröffentlichungen Lim, Hao, Shaw, Patel, Szabó, Rual, Fisk, Li, Smolyar, Hill, Barabási, Vidal, Zoghbi: "A protein-protein interaction network for human inherited ataxias and disorders of Purkinje cell degeneration." in: Cell, Vol. 125, Issue 4, pp. 801-14, 2006 (PubMed).

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