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Cytohesin 4 Antikörper (N-Term)

CYTH4 Reaktivität: Human, Maus, Ratte, Rind (Kuh), Schwein, Zebrafisch (Danio rerio), Hund, Meerschweinchen, Pferd, Kaninchen WB Wirt: Kaninchen Polyclonal unconjugated
Produktnummer ABIN2785970
  • Target Alle Cytohesin 4 (CYTH4) Antikörper anzeigen
    Cytohesin 4 (CYTH4)
    Bindungsspezifität
    • 9
    • 9
    • 7
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    N-Term
    Reaktivität
    Human, Maus, Ratte, Rind (Kuh), Schwein, Zebrafisch (Danio rerio), Hund, Meerschweinchen, Pferd, Kaninchen
    Wirt
    • 25
    • 2
    • 1
    Kaninchen
    Klonalität
    • 28
    Polyklonal
    Konjugat
    • 16
    • 3
    • 3
    • 2
    • 2
    • 2
    Dieser Cytohesin 4 Antikörper ist unkonjugiert
    Applikation
    • 26
    • 16
    • 2
    • 1
    • 1
    Western Blotting (WB)
    Sequenz
    NKTAIGTYLG ERDPINLQVL QAFVDCHEFA NLNLVQALRQ FLWSFRLPGE
    Homologie
    Cow: 100%, Dog: 93%, Guinea Pig: 86%, Horse: 93%, Human: 100%, Mouse: 93%, Pig: 100%, Rabbit: 93%, Rat: 93%, Zebrafish: 91%
    Produktmerkmale
    This is a rabbit polyclonal antibody against PSCD4. It was validated on Western Blot using a cell lysate as a positive control.
    Aufreinigung
    Affinity Purified
    Immunogen
    The immunogen is a synthetic peptide directed towards the N terminal region of human PSCD4
    Top Product
    Discover our top product CYTH4 Primärantikörper
  • Applikationshinweise
    Optimal working dilutions should be determined experimentally by the investigator.
    Kommentare

    Antigen size: 394 AA

    Beschränkungen
    Nur für Forschungszwecke einsetzbar
  • Format
    Liquid
    Konzentration
    Lot specific
    Buffer
    Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.
    Konservierungsmittel
    Sodium azide
    Vorsichtsmaßnahmen
    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    Handhabung
    Avoid repeated freeze-thaw cycles.
    Lagerung
    -20 °C
    Informationen zur Lagerung
    For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.
  • Target
    Cytohesin 4 (CYTH4)
    Andere Bezeichnung
    PSCD4 (CYTH4 Produkte)
    Synonyme
    zgc:175224 antikoerper, CYT4 antikoerper, DJ63G5.1 antikoerper, PSCD4 antikoerper, 2510004M07Rik antikoerper, 5830469K17Rik antikoerper, AI467541 antikoerper, Pscd4 antikoerper, mFLJ00017 antikoerper, RGD1564842 antikoerper, cytohesin-4 antikoerper, cytohesin 4b antikoerper, cytohesin 4 antikoerper, cyth4b antikoerper, CYTH4 antikoerper, Cyth4 antikoerper
    Hintergrund
    PSCD4 promotes guanine-nucleotide exchange on ARF1 and ARF5. PSCD4 promotes the activation of ARF through replacement of GDP with GTP.Pleckstrin homology, Sec7 and coiled/coil domains 4 (PSCD4) is a member of the PSCD family. Members of this family have identical structural organization that consists of an N-terminal coiled-coil motif, a central Sec7 domain, and a C-terminal pleckstrin homology (PH) domain. The coiled-coil motif is involved in homodimerization, the Sec7 domain contains guanine-nucleotide exchange protein (GEP) activity, and the PH domain interacts with phospholipids and is responsible for association of PSCDs with membranes. Members of this family appear to mediate the regulation of protein sorting and membrane trafficking. The PSCD4 exhibits GEP activity in vitro with both ARF1 and ARF5 but is inactive with ARF6. The PSCD4 and PSCD1 gene structures are very similar.
    Alias Symbols: CYT4, DJ63G5.1, PSCD4
    Protein Interaction Partner: KRT40, TRIM54, AMOTL2, SNAPC5, CNKSR1, KRT15, KIFC3, FOS, UBC, IPCEF1,
    Protein Size: 394
    Molekulargewicht
    46 kDa
    Gen-ID
    27128
    NCBI Accession
    NM_013385, NP_037517
    UniProt
    Q9UIA0
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