GTPBP4 Antikörper (C-Term)

Produktnummer ABIN2785935

Dieses Anti-GTPBP4-Antikörper ist ein Kaninchen Polyklonal-Antikörper zur Detektion von GTPBP4 in WB. Geeignet für Human, Maus, Ratte, Rind (Kuh), Hund, Pferd, Kaninchen und Meerschweinchen.

Kurzübersicht für GTPBP4 Antikörper (C-Term) (ABIN2785935)

Target: GTPBP4 (GTP Binding Protein 4 (GTPBP4))

Reaktivität: Human, Maus, Ratte, Rind (Kuh), Hund, Pferd, Kaninchen, Meerschweinchen

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser GTPBP4 Antikörper ist unkonjugiert

Applikation: Western Blotting (WB)

Produktdetails anti-GTPBP4 Antikörper

Bindungsspezifität: C-Term

Sequenz: MVKKAKTMMK NAQKKMNRLG KKGEADRHVF DMKPKHLLSG KRKAGKKDRR

Homologie: Cow: 100%, Dog: 100%, Guinea Pig: 100%, Horse: 100%, Human: 100%, Mouse: 100%, Rabbit: 100%, Rat: 100%

Produktmerkmale: This is a rabbit polyclonal antibody against GTPBP4. It was validated on Western Blot using a cell lysate as a positive control.

Aufreinigung: Affinity Purified

Immunogen: The immunogen is a synthetic peptide directed towards the C terminal region of human GTPBP4

Anwendungsinformationen

Applikationshinweise: Optimal working dilutions should be determined experimentally by the investigator.

Kommentare:

Antigen size: 634 AA

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Konzentration: Lot specific

Buffer: Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handhabung: Avoid repeated freeze-thaw cycles.

Lagerung: -20 °C

Informationen zur Lagerung: For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.

Details zu GTPBP4

Target: GTPBP4 (GTP Binding Protein 4 (GTPBP4))

Andere Bezeichnung: GTPBP4

Hintergrund: GTP-binding proteins are GTPases and function as molecular switches that can flip between two states: active, when GTP is bound, and inactive, when GDP is bound. 'Active' in this context usually means that the molecule acts as a signal to trigger other events in the cell. When an extracellular ligand binds to a G-protein-linked receptor, the receptor changes its conformation and switches on the trimeric G proteins that associate with it by causing them to eject their GDP and replace it with GTP. The switch is turned off when the G protein hydrolyzes its own bound GTP, converting it back to GDP. But before that occurs, the active protein has an opportunity to diffuse away from the receptor and deliver its message for a prolonged period to its downstream target.GTP-binding proteins are GTPases and function as molecular switches that can flip between two states: active, when GTP is bound, and inactive, when GDP is bound. 'Active' in this context usually means that the molecule acts as a signal to trigger other events in the cell. When an extracellular ligand binds to a G-protein-linked receptor, the receptor changes its conformation and switches on the trimeric G proteins that associate with it by causing them to eject their GDP and replace it with GTP. The switch is turned off when the G protein hydrolyzes its own bound GTP, converting it back to GDP. But before that occurs, the active protein has an opportunity to diffuse away from the receptor and deliver its message for a prolonged period to its downstream target.
Alias Symbols: CRFG, FLJ10686, FLJ10690, FLJ39774, NGB, NOG1
Protein Interaction Partner: SUMO3, UBC, POP1, PNMA2, PSME3, PRKRA, SUMO1, STAU1, NEDD8, EIF6, IFRD1, AZGP1, MRTO4, KCTD2, DICER1, SUZ12, EED, RNF2, CSNK2A2, CBX8, VCAM1, FN1, ESR1, UBD, CAND1, COPS5, SIRT7, SUMO2, EIF2AK2, OAS3, tat, TP53, YWHAG, LYAR, PINX1,
Protein Size: 634

Molekulargewicht: 74 kDa

Gen-ID: 23560

NCBI Accession: NM_012341, NP_036473

UniProt: Q9BZE4