PTGR1 Antikörper (N-Term)

Produktnummer ABIN2785929

Zitiert in 1 Publikation. Der Kaninchen Polyklonal anti-PTGR1 Antikörper (ABIN2785929) detektiert spezifisch PTGR1 in WB. Dieser Antikörper reagiert spezifisch mit Proben aus Human, Ratte, Kaninchen, Rind (Kuh), Meerschweinchen und Pferd.

Kurzübersicht für PTGR1 Antikörper (N-Term) (ABIN2785929)

Target: PTGR1 (Prostaglandin Reductase 1 (PTGR1))

Reaktivität: Human, Ratte, Kaninchen, Rind (Kuh), Meerschweinchen, Pferd

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser PTGR1 Antikörper ist unkonjugiert

Applikation: Western Blotting (WB)

Produktdetails anti-PTGR1 Antikörper

Bindungsspezifität: N-Term

Verwendungszweck: LTB4DH Antibody - N-terminal region

Sequenz: VRTKTWTLKK HFVGYPTNSD FELKTSELPP LKNGEVLLEA LFLTVDPYMR

Homologie: Cow: 93%, Guinea Pig: 83%, Horse: 83%, Human: 93%, Rabbit: 83%, Rat: 79%

Produktmerkmale: This is a rabbit polyclonal antibody against LTB4DH. It was validated on Western Blot using a cell lysate as a positive control.

Aufreinigung: Affinity Purified

Immunogen: The immunogen is a synthetic peptide directed towards the N terminal region of human LTB4DH

Anwendungsinformationen

Applikationshinweise: Optimal working dilution should be determined by the investigator.

Kommentare:

We also sell a specific blocking peptide that can be used in combination with this antibody. You can find the blocking peptide under AAP54865-100UG

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Konzentration: 0.5 mg/mL

Buffer: Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handhabung: prevent freeze-thaw cycles

Lagerung: 4 °C,-20 °C

Informationen zur Lagerung: For short term use, store at 2-8C up to 1 week. For long term storage, store at -20 °C in small aliquots to prevent freeze-thaw cycles.

Referenzen für anti-PTGR1 Antikörper (ABIN2785929)

Vitturi, Chen, Woodcock, Salvatore, Bonacci, Koenitzer, Stewart, Wakabayashi, Kensler, Freeman, Schopfer: "Modulation of nitro-fatty acid signaling: prostaglandin reductase-1 is a nitroalkene reductase." in: The Journal of biological chemistry, Vol. 288, Issue 35, pp. 25626-37, (2013) (PubMed).

Details zu PTGR1

Target: PTGR1 (Prostaglandin Reductase 1 (PTGR1))

Andere Bezeichnung: LTB4DH

Hintergrund:

Background Information: LTB4DH functions as 15-oxo-prostaglandin 13-reductase and acts on 15-oxo-PGE1, 15-oxo-PGE2 and 15-oxo-PGE2-alpha. It has no activity towards PGE1, PGE2 and PGE2-alpha. LTB4DH catalyzes the conversion of leukotriene B4 into its biologically less active metabolite, 12-oxo-leukotriene B4. This is an initial and key step of metabolic inactivation of leukotriene B4.

Gene Name: Prostaglandin reductase 1

Alternative Symbols: PGR1, DIG-1, ZADH3, LTB4DH

Protein Name: Prostaglandin reductase 1

Molekulargewicht: 36kDa

Gen-ID: 22949

NCBI Accession: NP_036344

UniProt: A8K0N2