ANGPTL2 Antikörper (N-Term)

Produktnummer ABIN503583

Zitiert in 2+ Publikationen. Der Kaninchen Polyklonal anti-ANGPTL2 Antikörper (ABIN503583) detektiert spezifisch ANGPTL2 in WB. Dieser Antikörper reagiert spezifisch mit Proben aus Human, Ratte, Maus, Rind (Kuh), Hund, Meerschweinchen, Pferd, Kaninchen und Zebrafisch (Danio rerio).

Kurzübersicht für ANGPTL2 Antikörper (N-Term) (ABIN503583)

Target: ANGPTL2 (Angiopoietin-Like 2 (ANGPTL2))

Reaktivität: Human, Ratte, Maus, Rind (Kuh), Hund, Meerschweinchen, Pferd, Kaninchen, Zebrafisch (Danio rerio)

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser ANGPTL2 Antikörper ist unkonjugiert

Applikation: Western Blotting (WB)

Produktdetails anti-ANGPTL2 Antikörper

Bindungsspezifität: N-Term

Verwendungszweck: ANGPTL2 Antibody - N-terminal region

Sequenz: NSKEPEVLLE NRVHKQELEL LNNELLKQKR QIETLQQLVE VDGGIVSEVK

Homologie: Cow: 100%, Dog: 100%, Guinea Pig: 100%, Horse: 100%, Human: 100%, Mouse: 100%, Rabbit: 100%, Rat: 100%, Zebrafish: 100%

Produktmerkmale: This is a rabbit polyclonal antibody against ANGPTL2. It was validated on Western Blot using a cell lysate as a positive control.

Aufreinigung: Affinity Purified

Immunogen: The immunogen is a synthetic peptide directed towards the N terminal region of human ANGPTL2

Anwendungsinformationen

Applikationshinweise: Optimal working dilution should be determined by the investigator.

Kommentare:

We also sell a specific blocking peptide that can be used in combination with this antibody. You can find the blocking peptide under AAP54835-100UG

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Konzentration: 0.5 mg/mL

Buffer: Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handhabung: prevent freeze-thaw cycles

Lagerung: 4 °C,-20 °C

Informationen zur Lagerung: For short term use, store at 2-8C up to 1 week. For long term storage, store at -20 °C in small aliquots to prevent freeze-thaw cycles.

Referenzen für anti-ANGPTL2 Antikörper (ABIN503583)

Doblinger, Höcherl, Mederle, Kattler, Walter, Hansen, Jensen, Castrop: "Angiotensin AT1 receptor-associated protein Arap1 in the kidney vasculature is suppressed by angiotensin II." in: American journal of physiology. Renal physiology, Vol. 302, Issue 10, pp. F1313-24, (2012) (PubMed).

Sun, Zheng, Chen, Zeng, Liu, Li: "Enhanced expression of ANGPTL2 in the microvascular lesions of diabetic glomerulopathy." in: Nephron. Experimental nephrology, Vol. 105, Issue 4, pp. e117-23, (2007) (PubMed).

Details zu ANGPTL2

Target: ANGPTL2 (Angiopoietin-Like 2 (ANGPTL2))

Andere Bezeichnung: ANGPTL2

Hintergrund:

Background Information: Angiopoietins are members of the vascular endothelial growth factor family and the only known growth factors largely specific for vascular endothelium. Angiopoietin-1, angiopoietin-2, and angiopoietin-4 participate in the formation of blood vessels. ANGPTL2 is a secreted glycoprotein with homology to the angiopoietins and may exert a function on endothelial cells through autocrine or paracrine action.Angiopoietins are members of the vascular endothelial growth factor family and the only known growth factors largely specific for vascular endothelium. Angiopoietin-1, angiopoietin-2, and angiopoietin-4 participate in the formation of blood vessels. ANGPTL2 protein is a secreted glycoprotein with homology to the angiopoietins and may exert a function on endothelial cells through autocrine or paracrine action. PRIMARYREFSEQ_SPAN PRIMARY_IDENTIFIER PRIMARY_SPAN COMP 1-127 AL598400.1 2-128 128-451 AL598400.1 129-452 452-2289 BC012368.1 325-2162 2290-3572 AK074726.1 1294-2576

Gene Name: Angiopoietin-like 2

Alternative Symbols: ARP2, HARP

Protein Name: Angiopoietin-related protein 2

Molekulargewicht: 57kDa

Gen-ID: 23452

NCBI Accession: NP_036230

UniProt: Q9UKU9