ANGPTL2 Antikörper (N-Term)
Kurzübersicht für ANGPTL2 Antikörper (N-Term) (ABIN2785913)
Target
Alle ANGPTL2 Antikörper anzeigenReaktivität
Wirt
Klonalität
Konjugat
Applikation
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Bindungsspezifität
- N-Term
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Sequenz
- NSKEPEVLLE NRVHKQELEL LNNELLKQKR QIETLQQLVE VDGGIVSEVK
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Homologie
- Cow: 100%, Dog: 100%, Guinea Pig: 100%, Horse: 100%, Human: 100%, Mouse: 100%, Rabbit: 100%, Rat: 100%, Zebrafish: 100%
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Produktmerkmale
- This is a rabbit polyclonal antibody against ANGPTL2. It was validated on Western Blot using a cell lysate as a positive control.
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Aufreinigung
- Affinity Purified
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Immunogen
- The immunogen is a synthetic peptide directed towards the N terminal region of human ANGPTL2
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Applikationshinweise
- Optimal working dilutions should be determined experimentally by the investigator.
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Kommentare
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Antigen size: 493 AA
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Beschränkungen
- Nur für Forschungszwecke einsetzbar
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Format
- Liquid
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Konzentration
- Lot specific
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Buffer
- Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.
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Konservierungsmittel
- Sodium azide
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Vorsichtsmaßnahmen
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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Handhabung
- Avoid repeated freeze-thaw cycles.
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Lagerung
- -20 °C
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Informationen zur Lagerung
- For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.
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: "Angiotensin AT1 receptor-associated protein Arap1 in the kidney vasculature is suppressed by angiotensin II." in: American journal of physiology. Renal physiology, Vol. 302, Issue 10, pp. F1313-24, (2012) (PubMed).
: "Enhanced expression of ANGPTL2 in the microvascular lesions of diabetic glomerulopathy." in: Nephron. Experimental nephrology, Vol. 105, Issue 4, pp. e117-23, (2007) (PubMed).
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: "Angiotensin AT1 receptor-associated protein Arap1 in the kidney vasculature is suppressed by angiotensin II." in: American journal of physiology. Renal physiology, Vol. 302, Issue 10, pp. F1313-24, (2012) (PubMed).
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- ANGPTL2 (Angiopoietin-Like 2 (ANGPTL2))
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Andere Bezeichnung
- ANGPTL2
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Hintergrund
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Angiopoietins are members of the vascular endothelial growth factor family and the only known growth factors largely specific for vascular endothelium. Angiopoietin-1, angiopoietin-2, and angiopoietin-4 participate in the formation of blood vessels. ANGPTL2 is a secreted glycoprotein with homology to the angiopoietins and may exert a function on endothelial cells through autocrine or paracrine action.Angiopoietins are members of the vascular endothelial growth factor family and the only known growth factors largely specific for vascular endothelium. Angiopoietin-1, angiopoietin-2, and angiopoietin-4 participate in the formation of blood vessels. ANGPTL2 protein is a secreted glycoprotein with homology to the angiopoietins and may exert a function on endothelial cells through autocrine or paracrine action. PRIMARYREFSEQ_SPAN PRIMARY_IDENTIFIER PRIMARY_SPAN COMP 1-127 AL598400.1 2-128 128-451 AL598400.1 129-452 452-2289 BC012368.1 325-2162 2290-3572 AK074726.1 1294-2576
Alias Symbols: ARP2, HARP, MGC8889
Protein Size: 493 -
Molekulargewicht
- 57 kDa
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Gen-ID
- 23452
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NCBI Accession
- NM_012098, NP_036230
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UniProt
- Q9UKU9
Target
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