COG2 Antikörper (N-Term)

Produktnummer ABIN2785901

Produktdetails anti-COG2 Antikörper

Target: COG2 (Conserved oligomeric Golgi complex subunit 2 (COG2))

Bindungsspezifität: N-Term

Reaktivität: Human, Maus, Ratte, Pferd, Kaninchen, Zebrafisch (Danio rerio), Rind (Kuh), Meerschweinchen

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser COG2 Antikörper ist unkonjugiert

Applikation: Western Blotting (WB)

Sequenz: KRVQLEELRD DLELYYKLLK TAMVELINKD YADFVNLSTN LVGMDKALNQ

Homologie: Cow: 93%, Guinea Pig: 86%, Horse: 100%, Human: 100%, Mouse: 100%, Rabbit: 100%, Rat: 100%, Zebrafish: 77%

Produktmerkmale: This is a rabbit polyclonal antibody against COG2. It was validated on Western Blot using a cell lysate as a positive control.

Aufreinigung: Affinity Purified

Immunogen: The immunogen is a synthetic peptide directed towards the N terminal region of human COG2

Anwendungsinformationen

Applikationshinweise: Optimal working dilutions should be determined experimentally by the investigator.

Kommentare:

Antigen size: 738 AA

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Konzentration: Lot specific

Buffer: Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handhabung: Avoid repeated freeze-thaw cycles.

Lagerung: -20 °C

Informationen zur Lagerung: For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.

Details zu COG2

Target: COG2 (Conserved oligomeric Golgi complex subunit 2 (COG2))

Andere Bezeichnung: COG2 (COG2 Produkte)

Hintergrund: Multiprotein complexes are key determinants of Golgi apparatus structure and its capacity for intracellular transport and glycoprotein modification. Several complexes have been identified, including the Golgi transport complex (GTC), the LDLC complex, which is involved in glycosylation reactions, and the SEC34 complex, which is involved in vesicular transport. These 3 complexes are identical and have been termed the conserved oligomeric Golgi (COG) complex, which includes COG2. Multiprotein complexes are key determinants of Golgi apparatus structure and its capacity for intracellular transport and glycoprotein modification. Several complexes have been identified, including the Golgi transport complex (GTC), the LDLC complex, which is involved in glycosylation reactions, and the SEC34 complex, which is involved in vesicular transport. These 3 complexes are identical and have been termed the conserved oligomeric Golgi (COG) complex, which includes COG2 (Ungar et al., 2002 [PubMed 11980916]).[supplied by OMIM].
Alias Symbols: LDLC
Protein Interaction Partner: MTUS2, UBC, COG7, COG8, COG3, COG6, COG5, COG1, COG4,
Protein Size: 738

Molekulargewicht: 83 kDa

Gen-ID: 22796

NCBI Accession: NM_007357, NP_031383

UniProt: Q14746