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INPP5B Antikörper (Middle Region)

INPP5B Reaktivität: Human, Maus, Ratte, Hund, Kaninchen, Pferd, Meerschweinchen WB Wirt: Kaninchen Polyclonal unconjugated
Produktnummer ABIN2785875
  • Target Alle INPP5B Antikörper anzeigen
    INPP5B (Inositol Polyphosphate-5-Phosphatase, 75kDa (INPP5B))
    Bindungsspezifität
    • 9
    • 8
    • 7
    • 5
    • 4
    • 1
    • 1
    Middle Region
    Reaktivität
    Human, Maus, Ratte, Hund, Kaninchen, Pferd, Meerschweinchen
    Wirt
    • 34
    • 2
    Kaninchen
    Klonalität
    • 36
    Polyklonal
    Konjugat
    • 15
    • 4
    • 4
    • 3
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    Dieser INPP5B Antikörper ist unkonjugiert
    Applikation
    • 23
    • 18
    • 17
    • 14
    • 5
    • 2
    • 1
    Western Blotting (WB)
    Sequenz
    IHNGQVPCHF EFINKPDEES YCKQWLNANP SRGFLLPDSD VEIDLELFVN
    Homologie
    Dog: 85%, Guinea Pig: 92%, Horse: 92%, Human: 100%, Mouse: 92%, Rabbit: 77%, Rat: 92%
    Produktmerkmale
    This is a rabbit polyclonal antibody against INPP5B. It was validated on Western Blot using a cell lysate as a positive control.
    Aufreinigung
    Affinity Purified
    Immunogen
    The immunogen is a synthetic peptide directed towards the middle region of human INPP5B
    Top Product
    Discover our top product INPP5B Primärantikörper
  • Applikationshinweise
    Optimal working dilutions should be determined experimentally by the investigator.
    Kommentare

    Antigen size: 913 AA

    Beschränkungen
    Nur für Forschungszwecke einsetzbar
  • Format
    Liquid
    Konzentration
    Lot specific
    Buffer
    Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.
    Konservierungsmittel
    Sodium azide
    Vorsichtsmaßnahmen
    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    Handhabung
    Avoid repeated freeze-thaw cycles.
    Lagerung
    -20 °C
    Informationen zur Lagerung
    For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.
  • Tothova, Kollipara, Huntly, Lee, Castrillon, Cullen, McDowell, Lazo-Kallanian, Williams, Sears, Armstrong, Passegué, DePinho, Gilliland: "FoxOs are critical mediators of hematopoietic stem cell resistance to physiologic oxidative stress." in: Cell, Vol. 128, Issue 2, pp. 325-39, (2007) (PubMed).

  • Target
    INPP5B (Inositol Polyphosphate-5-Phosphatase, 75kDa (INPP5B))
    Andere Bezeichnung
    INPP5B (INPP5B Produkte)
    Synonyme
    75kDa antikoerper, AW260155 antikoerper, INPP5P antikoerper, 5PTase antikoerper, inositol polyphosphate-5-phosphatase B antikoerper, type II inositol 1,4,5-trisphosphate 5-phosphatase-like antikoerper, inositol polyphosphate-5-phosphatase B L homeolog antikoerper, inositol polyphosphate 5-phosphatase OCRL-1 antikoerper, INPP5B antikoerper, LOC100224437 antikoerper, inpp5b.L antikoerper, LOC100159919 antikoerper, Inpp5b antikoerper
    Hintergrund
    Cellular calcium signaling is controlled by the production of inositol phosphates (IPs) by phospholipase C in response to extracellular signals. The IP signaling molecules are inactivated by a family of inositol polyphosphate-5-phosphatases (5-phosphatases). INPP5B is the type II 5-phosphatase. The protein is localized to the cytosol and mitochondria, and associates with membranes through an isoprenyl modification near the C-terminus.Cellular calcium signaling is controlled by the production of inositol phosphates (IPs) by phospholipase C in response to extracellular signals. The IP signaling molecules are inactivated by a family of inositol polyphosphate-5-phosphatases (5-phosphatases). This gene encodes the type II 5-phosphatase. The protein is localized to the cytosol and mitochondria, and associates with membranes through an isoprenyl modification near the C-terminus. Several alternatively spliced transcript variants of this gene have been described, but the full-length nature of some of these variants has not been determined.
    Alias Symbols: 5PTase, MGC65156, MGC71303
    Protein Interaction Partner: UBC, APP, SMURF1,
    Protein Size: 913
    Molekulargewicht
    77 kDa
    Gen-ID
    3633
    NCBI Accession
    NM_005540, NP_005531
    UniProt
    P32019
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