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HADH Antikörper (C-Term)

Dieses Anti-HADH-Antikörper ist ein Kaninchen Polyklonal-Antikörper zur Detektion von HADH in WB und IHC. Geeignet für Human, Maus, Ratte, Zebrafisch (Danio rerio), Hund, Meerschweinchen, Pferd, Kaninchen, Rind (Kuh) und Saccharomyces cerevisiae.
Produktnummer ABIN2785872

Kurzübersicht für HADH Antikörper (C-Term) (ABIN2785872)

Target

Alle HADH Antikörper anzeigen
HADH (Hydroxyacyl-CoA Dehydrogenase (HADH))

Reaktivität

  • 40
  • 37
  • 22
  • 7
  • 5
  • 2
  • 2
  • 2
  • 2
  • 2
  • 1
  • 1
Human, Maus, Ratte, Zebrafisch (Danio rerio), Hund, Meerschweinchen, Pferd, Kaninchen, Rind (Kuh), Saccharomyces cerevisiae

Wirt

  • 41
  • 14
  • 1
  • 1
Kaninchen

Klonalität

  • 44
  • 13
Polyklonal

Konjugat

  • 28
  • 4
  • 2
  • 2
  • 2
  • 2
  • 2
  • 2
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
Dieser HADH Antikörper ist unkonjugiert

Applikation

  • 42
  • 15
  • 15
  • 13
  • 13
  • 12
  • 9
  • 9
  • 8
  • 3
  • 2
  • 2
  • 2
  • 2
  • 1
Western Blotting (WB), Immunohistochemistry (IHC)
  • Bindungsspezifität

    • 15
    • 4
    • 3
    • 3
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    C-Term

    Sequenz

    YPMGPFELLD YVGLDTTKFI VDGWHEMDAE NPLHQPSPSL NKLVAENKFG

    Homologie

    Cow: 100%, Dog: 100%, Guinea Pig: 100%, Horse: 100%, Human: 100%, Mouse: 100%, Rabbit: 100%, Rat: 100%, Yeast: 85%, Zebrafish: 93%

    Produktmerkmale

    This is a rabbit polyclonal antibody against HADH. It was validated on Western Blot using a cell lysate as a positive control.

    Aufreinigung

    Affinity Purified

    Immunogen

    The immunogen is a synthetic peptide directed towards the C terminal region of human HADH
  • Applikationshinweise

    Optimal working dilutions should be determined experimentally by the investigator.

    Kommentare

    Antigen size: 314 AA

    Beschränkungen

    Nur für Forschungszwecke einsetzbar
  • Format

    Liquid

    Konzentration

    Lot specific

    Buffer

    Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.

    Konservierungsmittel

    Sodium azide

    Vorsichtsmaßnahmen

    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

    Handhabung

    Avoid repeated freeze-thaw cycles.

    Lagerung

    -20 °C

    Informationen zur Lagerung

    For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.
  • Target

    HADH (Hydroxyacyl-CoA Dehydrogenase (HADH))

    Andere Bezeichnung

    HADH

    Hintergrund

    HADH functions in the mitochondrial matrix to catalyze the oxidation of straight-chain 3-hydroxyacyl-CoAs as part of the beta-oxidation pathway. Its enzymatic activity is highest with medium-chain-length fatty acids. Mutations in this gene cause one form of familial hyperinsulinemic hypoglycemia. This gene is a member of the 3-hydroxyacyl-CoA dehydrogenase gene family. The encoded protein functions in the mitochondrial matrix to catalyze the oxidation of straight-chain 3-hydroxyacyl-CoAs as part of the beta-oxidation pathway. Its enzymatic activity is highest with medium-chain-length fatty acids. Mutations in this gene cause one form of familial hyperinsulinemic hypoglycemia. The human genome contains a related pseudogene. Publication Note: This RefSeq record includes a subset of the publications that are available for this gene. Please see the Entrez Gene record to access additional publications.
    Alias Symbols: HAD, HADH1, HADHSC, HHF4, M/SCHAD, MGC8392, SCHAD, HCDH, MSCHAD
    Protein Interaction Partner: MDM2, STAT1, ADH1A, APP, UBC, MAPK3, UBA5, HADH, SLC2A4,
    Protein Size: 314

    Molekulargewicht

    33 kDa

    Gen-ID

    3033

    NCBI Accession

    NM_005327, NP_005318

    UniProt

    Q16836

    Pathways

    Negative Regulation of Hormone Secretion, Monocarboxylic Acid Catabolic Process
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