Histone Cluster 1, H1t (HIST1H1T) (Middle Region) Antikörper

Produktnummer ABIN2785870

Produktdetails

Target: Histone Cluster 1, H1t (HIST1H1T)

Bindungsspezifität: Middle Region

Reaktivität: Human, Hund, Schwein, Kaninchen

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Unkonjugiert

Applikation: Western Blotting (WB)

Sequenz: KLSKKVIPKS TRSKAKKSVS AKTKKLVLSR DSKSPKTAKT NKRAKKPRAT

Homologie: Dog: 92%, Human: 100%, Pig: 86%, Rabbit: 93%

Produktmerkmale: This is a rabbit polyclonal antibody against HIST1H1T. It was validated on Western Blot using a cell lysate as a positive control.

Aufreinigung: Affinity Purified

Immunogen: The immunogen is a synthetic peptide directed towards the middle region of human HIST1H1T

Anwendungsinformationen

Applikationshinweise: Optimal working dilutions should be determined experimentally by the investigator.

Kommentare:

Antigen size: 207 AA

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Konzentration: Lot specific

Buffer: Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handhabung: Avoid repeated freeze-thaw cycles.

Lagerung: -20 °C

Informationen zur Lagerung: For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.

Antigendetails

Target: Histone Cluster 1, H1t (HIST1H1T)

Andere Bezeichnung: HIST1H1T (HIST1H1T Produkte)

Hintergrund: Histones are basic nuclear proteins responsible for nucleosome structure of the chromosomal fiber in eukaryotes. Two molecules of each of the four core histones (H2A, H2B, H3, and H4) form an octamer, around which approximately 146 bp of DNA is wrapped in repeating units, called nucleosomes. The linker histone, H1, interacts with linker DNA between nucleosomes and functions in the compaction of chromatin into higher order structures. HIST1H1T is a member of the histone H1 family. Histones are basic nuclear proteins responsible for nucleosome structure of the chromosomal fiber in eukaryotes. Two molecules of each of the four core histones (H2A, H2B, H3, and H4) form an octamer, around which approximately 146 bp of DNA is wrapped in repeating units, called nucleosomes. The linker histone, H1, interacts with linker DNA between nucleosomes and functions in the compaction of chromatin into higher order structures. This gene is intronless and encodes a member of the histone H1 family. Transcripts from this gene lack polyA tails but instead contain a palindromic termination element. This gene is found in the large histone gene cluster on chromosome 6.
Alias Symbols: H1FT, H1t, MGC163222, dJ221C16.2
Protein Interaction Partner: UBC, SUMO1, IRAK4, PRKCA, YWHAQ, POU5F1,
Protein Size: 207

Molekulargewicht: 22 kDa

Gen-ID: 3010

NCBI Accession: NM_005323, NP_005314

UniProt: P22492