Histone H1 Antikörper (N-Term)

Produktnummer ABIN2785869

Dieses Kaninchen Polyklonal-Antikörper erkennt spezifisch Histone H1 in WB. Er zeigt eine Reaktivität gegenüber Human, Maus, Ratte, Rind (Kuh) und Meerschweinchen.

Kurzübersicht für Histone H1 Antikörper (N-Term) (ABIN2785869)

Target: Histone H1 (H1F0) (H1 Histone Family, Member 0 (H1F0))

Reaktivität: Human, Maus, Ratte, Rind (Kuh), Meerschweinchen

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser Histone H1 Antikörper ist unkonjugiert

Applikation: Western Blotting (WB)

Produktdetails anti-Histone H1 Antikörper

Bindungsspezifität: N-Term

Sequenz: IQAEKNRAGS SRQSIQKYIK SHYKVGENAD SQIKLSIKRL VTTGVLKQTK

Homologie: Cow: 100%, Guinea Pig: 100%, Human: 100%, Mouse: 100%, Rat: 100%

Produktmerkmale: This is a rabbit polyclonal antibody against H1F0. It was validated on Western Blot using a cell lysate as a positive control.

Aufreinigung: Affinity Purified

Immunogen: The immunogen is a synthetic peptide directed towards the N terminal region of human H1F0

Anwendungsinformationen

Applikationshinweise: Optimal working dilutions should be determined experimentally by the investigator.

Kommentare:

Antigen size: 194 AA

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Konzentration: Lot specific

Buffer: Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handhabung: Avoid repeated freeze-thaw cycles.

Lagerung: -20 °C

Informationen zur Lagerung: For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.

Details zu Histone H1

Target: Histone H1 (H1F0) (H1 Histone Family, Member 0 (H1F0))

Andere Bezeichnung: H1F0

Hintergrund: Histones are basic nuclear proteins that are responsible for the nucleosome structure of the chromosomal fiber in eukaryotes. Nucleosomes consist of approximately 146 bp of DNA wrapped around a histone octamer composed of pairs of each of the four core histones (H2A, H2B, H3, and H4). The chromatin fiber is further compacted through the interaction of a linker histone, H1, with the DNA between the nucleosomes to form higher order chromatin structures. H1F0 gene is intronless and encodes a member of the histone H1 family.Histones are basic nuclear proteins that are responsible for the nucleosome structure of the chromosomal fiber in eukaryotes. Nucleosomes consist of approximately 146 bp of DNA wrapped around a histone octamer composed of pairs of each of the four core histones (H2A, H2B, H3, and H4). The chromatin fiber is further compacted through the interaction of a linker histone, H1, with the DNA between the nucleosomes to form higher order chromatin structures. This gene is intronless and encodes a member of the histone H1 family. Publication Note: This RefSeq record includes a subset of the publications that are available for this gene. Please see the Entrez Gene record to access additional publications.
Alias Symbols: H10, H1FV, MGC5241
Protein Interaction Partner: UBC, LIN28A, POP1, PRKRA, SUZ12, EED, RNF2, PARK2, ERCC8, PRKCB, CDK1, APP, CDK2, CDK4, CAND1, PfPK6, YWHAZ, CDK5, CCNE1, HDGF, Nedd4, NEDD4L, GRB2, YWHAQ, XBP1, IKBKG, NOA1, IPO7, RAD51B, KPNB1, IPO5, KPNA2,
Protein Size: 194

Molekulargewicht: 21 kDa

Gen-ID: 3005

NCBI Accession: NM_005318, NP_005309

UniProt: P07305