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ICA1 Antikörper (C-Term)

This anti-ICA1 antibody (ABIN2785862) is a Rabbit Polyclonal antibody detecting ICA1 in WB. Suitable for Human, Mouse, Rat, Dog, Guinea Pig, Horse, Cow, Rabbit.
Produktnummer ABIN2785862

Kurzübersicht für ICA1 Antikörper (C-Term) (ABIN2785862)

Target

Alle ICA1 Antikörper anzeigen
ICA1 (Islet Cell Autoantigen 1, 69kDa (ICA1))

Reaktivität

  • 63
  • 15
  • 5
  • 3
  • 3
  • 3
  • 2
  • 2
  • 2
  • 2
  • 2
  • 1
  • 1
  • 1
Human, Maus, Ratte, Hund, Meerschweinchen, Pferd, Rind (Kuh), Kaninchen

Wirt

  • 63
  • 7
Kaninchen

Klonalität

  • 64
  • 6
Polyklonal

Konjugat

  • 31
  • 12
  • 5
  • 3
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
Dieser ICA1 Antikörper ist unkonjugiert

Applikation

  • 60
  • 22
  • 20
  • 13
  • 13
  • 11
  • 6
  • 6
  • 3
  • 3
  • 1
Western Blotting (WB)
  • Bindungsspezifität

    • 15
    • 8
    • 7
    • 5
    • 5
    • 3
    • 2
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    C-Term

    Sequenz

    NMKDLQASLQ EPAKAASDLT AWFSLFADLD PLSNPDAVGK TDKEHELLNA

    Homologie

    Cow: 93%, Dog: 100%, Guinea Pig: 100%, Horse: 100%, Human: 100%, Mouse: 100%, Rabbit: 100%, Rat: 100%

    Produktmerkmale

    This is a rabbit polyclonal antibody against ICA1. It was validated on Western Blot using a cell lysate as a positive control.

    Aufreinigung

    Affinity Purified

    Immunogen

    The immunogen is a synthetic peptide directed towards the C terminal region of human ICA1
  • Applikationshinweise

    Optimal working dilutions should be determined experimentally by the investigator.

    Kommentare

    Antigen size: 483 AA

    Beschränkungen

    Nur für Forschungszwecke einsetzbar
  • Format

    Liquid

    Konzentration

    Lot specific

    Buffer

    Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.

    Konservierungsmittel

    Sodium azide

    Vorsichtsmaßnahmen

    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

    Handhabung

    Avoid repeated freeze-thaw cycles.

    Lagerung

    -20 °C

    Informationen zur Lagerung

    For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.
  • Ewing, Chu, Elisma, Li, Taylor, Climie, McBroom-Cerajewski, Robinson, OConnor, Li, Taylor, Dharsee, Ho, Heilbut, Moore, Zhang, Ornatsky, Bukhman, Ethier, Sheng, Vasilescu, Abu-Farha, Lambert, Duewel et al.: "Large-scale mapping of human protein-protein interactions by mass spectrometry. ..." in: Molecular systems biology, Vol. 3, pp. 89, (2007) (PubMed).

  • Target

    ICA1 (Islet Cell Autoantigen 1, 69kDa (ICA1))

    Andere Bezeichnung

    ICA1

    Hintergrund

    ICA1 is a protein with an arfaptin homology domain that is found both in the cytosol and as membrane-bound form on the Golgi complex and immature secretory granules. This protein is believed to be an autoantigen in insulin-dependent diabetes mellitus and primary Sjogren's syndrome. This gene encodes a protein with an arfaptin homology domain that is found both in the cytosol and as membrane-bound form on the Golgi complex and immature secretory granules. This protein is believed to be an autoantigen in insulin-dependent diabetes mellitus and primary Sjogren's syndrome. Alternatively spliced variants which encode different protein isoforms have been described, however, not all variants have been fully characterized.
    Alias Symbols: ICA69, ICAp69
    Protein Interaction Partner: RAB2B, ING5, MBD3, CCDC28A, RAB2A, tbc-8, EXOC5, STK16, MKKS, KRT33B, CNTF,
    Protein Size: 483

    Molekulargewicht

    53 kDa

    Gen-ID

    3382

    NCBI Accession

    NM_022307, NP_071682

    UniProt

    Q05084
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