IDI1 Antikörper (Middle Region)

Produktnummer ABIN2785856

Dieser Kaninchen Polyklonal Antikörper detektiert spezifisch IDI1 in WB. Es zeigt Reaktivität gegenüber Proben von Human, Maus, Ratte, Meerschweinchen, Pferd, Rind (Kuh), Hund und Kaninchen.

Kurzübersicht für IDI1 Antikörper (Middle Region) (ABIN2785856)

Target: IDI1 (Isopentenyl-Diphosphate delta Isomerase 1 (IDI1))

Reaktivität: Human, Maus, Ratte, Meerschweinchen, Pferd, Rind (Kuh), Hund, Kaninchen

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser IDI1 Antikörper ist unkonjugiert

Applikation: Western Blotting (WB)

Produktdetails anti-IDI1 Antikörper

Bindungsspezifität: Middle Region

Verwendungszweck: IDI1 Antibody - middle region

Sequenz: PLSNPAELEE SDALGVRRAA QRRLKAELGI PLEEVPPEEI NYLTRIHYKA

Homologie: Cow: 93%, Dog: 86%, Guinea Pig: 100%, Horse: 86%, Human: 100%, Mouse: 100%, Rabbit: 93%, Rat: 100%

Produktmerkmale: This is a rabbit polyclonal antibody against IDI1. It was validated on Western Blot using a cell lysate as a positive control.

Aufreinigung: Affinity Purified

Immunogen: The immunogen is a synthetic peptide directed towards the middle region of human IDI1

Anwendungsinformationen

Applikationshinweise: Optimal working dilution should be determined by the investigator.

Kommentare:

We also sell a specific blocking peptide that can be used in combination with this antibody. You can find the blocking peptide under AAP54735-100UG

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Konzentration: 0.5 mg/mL

Buffer: Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handhabung: prevent freeze-thaw cycles

Lagerung: 4 °C,-20 °C

Informationen zur Lagerung: For short term use, store at 2-8C up to 1 week. For long term storage, store at -20 °C in small aliquots to prevent freeze-thaw cycles.

Details zu IDI1

Target: IDI1 (Isopentenyl-Diphosphate delta Isomerase 1 (IDI1))

Andere Bezeichnung: IDI1

Hintergrund:

Background Information: IDI1 is a peroxisomally-localized enzyme that catalyzes the interconversion of isopentenyl diphosphate (IPP) to its highly electrophilic isomer, dimethylallyl diphosphate (DMAPP), which are the substrates for the successive reaction that results in the synthesis of farnesyl diphosphate and, ultimately, cholesterol. It has been shown in peroxisomal deficiency diseases such as Zellweger syndrome and neonatal adrenoleukodystrophy that there is reduction in IPP isomerase activity.IDI1 encodes a peroxisomally-localized enzyme that catalyzes the interconversion of isopentenyl diphosphate (IPP) to its highly electrophilic isomer, dimethylallyl diphosphate (DMAPP), which are the substrates for the successive reaction that results in the synthesis of farnesyl diphosphate and, ultimately, cholesterol. It has been shown in peroxisomal deficiency diseases such as Zellweger syndrome and neonatal adrenoleukodystrophy that there is reduction in IPP isomerase activity. PRIMARYREFSEQ_SPAN PRIMARY_IDENTIFIER PRIMARY_SPAN COMP 1-492 BE891119.1 50-541 493-1758 BX648472.1 1201-2466 1759-2150 BX537663.1 4550-4941

Gene Name: Isopentenyl-diphosphate delta isomerase 1

Alternative Symbols: IPP1, IPPI1

Protein Name: Isopentenyl-diphosphate Delta-isomerase 1

Molekulargewicht: 32kDa

Gen-ID: 3422

NCBI Accession: NP_004499

UniProt: Q13907