IDH3G Antikörper (C-Term)

Produktnummer ABIN2785851

Der Kaninchen Polyklonal anti-IDH3G Antikörper wird verwendet zum Nachweis von IDH3G in Proben von Human, Maus, Ratte, Rind (Kuh), Hund, Pferd, Ziege, Meerschweinchen, Kaninchen, Saccharomyces cerevisiae und Zebrafisch (Danio rerio). Er wurde validiert für WB.

Kurzübersicht für IDH3G Antikörper (C-Term) (ABIN2785851)

Target: IDH3G (Isocitrate Dehydrogenase 3 (NAD+) gamma (IDH3G))

Reaktivität: Human, Maus, Ratte, Rind (Kuh), Hund, Pferd, Ziege, Meerschweinchen, Kaninchen, Saccharomyces cerevisiae, Zebrafisch (Danio rerio)

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser IDH3G Antikörper ist unkonjugiert

Applikation: Western Blotting (WB)

Produktdetails anti-IDH3G Antikörper

Bindungsspezifität: C-Term

Verwendungszweck: IDH3G Antibody - C-terminal region

Sequenz: YMTRHNNLDL VIIREQTEGE YSSLEHEVRP QKLGEGKDED GREVELLVSL

Homologie: Cow: 100%, Dog: 100%, Goat: 93%, Guinea Pig: 100%, Horse: 100%, Human: 100%, Mouse: 100%, Rabbit: 100%, Rat: 100%, Yeast: 93%, Zebrafish: 100%

Produktmerkmale: This is a rabbit polyclonal antibody against IDH3B. It was validated on Western Blot.

Aufreinigung: Affinity Purified

Immunogen: The immunogen is a synthetic peptide directed towards the C-terminal region of human IDH3G

Anwendungsinformationen

Applikationshinweise: Optimal working dilution should be determined by the investigator.

Kommentare:

We also sell a specific blocking peptide that can be used in combination with this antibody. You can find the blocking peptide under AAP54721-100UG

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Konzentration: 0.5 mg/mL

Buffer: Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handhabung: prevent freeze-thaw cycles

Lagerung: 4 °C,-20 °C

Informationen zur Lagerung: For short term use, store at 2-8C up to 1 week. For long term storage, store at -20 °C in small aliquots to prevent freeze-thaw cycles.

Details zu IDH3G

Target: IDH3G (Isocitrate Dehydrogenase 3 (NAD+) gamma (IDH3G))

Andere Bezeichnung: IDH3G

Hintergrund:

Background Information: Isocitrate dehydrogenases catalyze the oxidative decarboxylation of isocitrate to 2-oxoglutarate. These enzymes belong to two distinct subclasses, one of which utilizes NAD(+) as the electron acceptor and the other NADP(+). Five isocitrate dehydrogenases have been reported: three NAD(+)-dependent isocitrate dehydrogenases, which localize to the mitochondrial matrix, and two NADP(+)-dependent isocitrate dehydrogenases, one of which is mitochondrial and the other predominantly cytosolic. NAD(+)-dependent isocitrate dehydrogenases catalyze the allosterically regulated rate-limiting step of the tricarboxylic acid cycle. Each isozyme is a heterotetramer that is composed of two alpha subunits, one beta subunit, and one gamma subunit. The protein encoded by this gene is the gamma subunit of one isozyme of NAD(+)-dependent isocitrate dehydrogenase. This gene is a candidate gene for periventricular heterotopia. Several alternatively spliced transcript variants of this gene have been described, but only some of their full length natures have been determined.

Gene Name: isocitrate dehydrogenase 3 (NAD+) gamma

Alternative Symbols: H-IDHG

Protein Name: isocitrate dehydrogenase [NAD] subunit gamma, mitochondrial

Molekulargewicht: 22kDa

Gen-ID: 3421

NCBI Accession: NP_004126

UniProt: P51553