FKBP5 Antikörper (Middle Region)
Kurzübersicht für FKBP5 Antikörper (Middle Region) (ABIN2785845)
Target
Alle FKBP5 Antikörper anzeigenReaktivität
Wirt
Klonalität
Konjugat
Applikation
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Bindungsspezifität
- Middle Region
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Sequenz
- KMQREEQCIL YLGPRYGFGE AGKPKFGIEP NAELIYEVTL KSFEKAKESW
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Homologie
- Cow: 100%, Dog: 100%, Guinea Pig: 92%, Horse: 100%, Human: 100%, Mouse: 100%, Pig: 100%, Rabbit: 100%, Rat: 100%
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Produktmerkmale
- This is a rabbit polyclonal antibody against FKBP5. It was validated on Western Blot.
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Aufreinigung
- Affinity Purified
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Immunogen
- The immunogen is a synthetic peptide directed towards the middle region of Human FKBP5
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Beschränkungen
- Nur für Forschungszwecke einsetzbar
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Format
- Liquid
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Konzentration
- 1 mg/mL
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Buffer
- Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.
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Konservierungsmittel
- Sodium azide
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Vorsichtsmaßnahmen
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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Handhabung
- Avoid repeat freeze-thaw cycles.
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Lagerung
- -20 °C
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Informationen zur Lagerung
- For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.
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- FKBP5 (FK506 Binding Protein 5 (FKBP5))
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Andere Bezeichnung
- FKBP5
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Hintergrund
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The protein encoded by this gene is a member of the immunophilin protein family, which play a role in immunoregulation and basic cellular processes involving protein folding and trafficking. This encoded protein is a cis-trans prolyl isomerase that binds to the immunosuppressants FK506 and rapamycin. It is thought to mediate calcineurin inhibition. It also interacts functionally with mature hetero-oligomeric progesterone receptor complexes along with the 90 kDa heat shock protein and P23 protein. This gene has been found to have multiple polyadenylation sites.
Alias Symbols: AIG6, FKBP51, FKBP54, P54, PPIase, Ptg-10
Protein Interaction Partner: LRRC40, CXorf57, EGLN1, AGO2, CACYBP, CHORDC1, AGO1, KIAA1279, NUDCD3, GLMN, CDC37, SUGT1, PTGES3, NUDC, AHSA1, DNAJB6, AURKB, IKBKG, IRS4, TUBA1A, TTC4, PYGL, PDCD2, CDK11A, HGH1, C14orf80, MCMBP, PNPLA2, ANKMY2, CDC37L1, MCM4, ILK, HSP90AB1, HSP90AA1, H
Protein Size: 457 -
Molekulargewicht
- 51 kDa
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Gen-ID
- 2289
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NCBI Accession
- NM_004117, NP_004108
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UniProt
- Q13451
Target
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