RHOB Antikörper (Middle Region)

Produktnummer ABIN2785839

Produktdetails anti-RHOB Antikörper

Target: RHOB (Ras Homolog Gene Family, Member B (RHOB))

Bindungsspezifität: Middle Region

Reaktivität: Human, Maus, Ratte, Ziege, Pferd, Schwein, Schaf, Rind (Kuh), Meerschweinchen, Kaninchen, Zebrafisch (Danio rerio), Hund

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser RHOB Antikörper ist unkonjugiert

Applikation: Western Blotting (WB)

Sequenz: CPNVPIILVA NKKDLRSDEH VRTELARMKQ EPVRTDDGRA MAVRIQAYDY

Homologie: Cow: 100%, Dog: 100%, Goat: 100%, Guinea Pig: 79%, Horse: 100%, Human: 100%, Mouse: 100%, Pig: 100%, Rabbit: 79%, Rat: 100%, Sheep: 100%, Zebrafish: 79%

Produktmerkmale: This is a rabbit polyclonal antibody against RHOB. It was validated on Western Blot using a cell lysate as a positive control.

Aufreinigung: Affinity Purified

Immunogen: The immunogen is a synthetic peptide directed towards the middle region of human RHOB

Anwendungsinformationen

Applikationshinweise: Optimal working dilutions should be determined experimentally by the investigator.

Kommentare:

Antigen size: 196 AA

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Konzentration: Lot specific

Buffer: Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handhabung: Avoid repeated freeze-thaw cycles.

Lagerung: -20 °C

Informationen zur Lagerung: For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.

Details zu RHOB

Target: RHOB (Ras Homolog Gene Family, Member B (RHOB))

Andere Bezeichnung: RHOB (RHOB Produkte)

Synonyme: ARH6 antikoerper, ARHB antikoerper, MST081 antikoerper, MSTP081 antikoerper, RHOH6 antikoerper, AA017882 antikoerper, Arh6 antikoerper, Arhb antikoerper, RHO antikoerper, arha antikoerper, rhoa antikoerper, wu:fj42e08 antikoerper, zgc:92206 antikoerper, rhob antikoerper, xrhob antikoerper, ras homolog family member B antikoerper, ras homolog gene family, member Ab antikoerper, ras homolog family member B S homeolog antikoerper, RHOB antikoerper, Rhob antikoerper, rhoab antikoerper, rhob.S antikoerper

Hintergrund: RHOB mediates apoptosis in neoplastically transformed cells after DNA damage.RHOB is not essential for development but affects cell adhesion and growth factor signaling in transformed cells.RHOB plays a negative role in tumorigenesis as deletion causes tumor formation. RHOB is involved in intracellular protein trafficking of a number of proteins.RHOB targets PKN1 to endosomes and is involved in trafficking of the EGF receptor from late endosomes to lysosomes.RHOB is also required for stability and nuclear trafficking of AKT1/AKT which promotes endothelial cell survival during vascular development.
Alias Symbols: ARH6, ARHB, MST081, MSTP081, RHOH6
Protein Interaction Partner: RAC1, MDM2, UBC, CORO1C, LAMTOR3, ILF2, HNRNPU, TNFAIP1, ELAVL1, ARHGEF3, RHPN2, PPP2CA, ARHGDIG, PDE6D, PGGT1B, FNTA, CIT,
Protein Size: 196

Molekulargewicht: 22 kDa

Gen-ID: 388

NCBI Accession: NM_004040, NP_004031

UniProt: P62745