LCP1 Antikörper (C-Term)

Produktnummer ABIN2785831

Der Kaninchen Polyklonal anti-LCP1 Antikörper (ABIN2785831) detektiert spezifisch LCP1 in WB. Dieser Antikörper reagiert spezifisch mit Proben aus Human, Maus, Ratte, Zebrafisch (Danio rerio), Rind (Kuh), Hund, Meerschweinchen, Pferd, Kaninchen und Schwein.

Kurzübersicht für LCP1 Antikörper (C-Term) (ABIN2785831)

Target: LCP1 (Lymphocyte Cytosolic Protein 1 (LCP1))

Reaktivität: Human, Maus, Ratte, Zebrafisch (Danio rerio), Rind (Kuh), Hund, Meerschweinchen, Pferd, Kaninchen, Schwein

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser LCP1 Antikörper ist unkonjugiert

Applikation: Western Blotting (WB)

Produktdetails anti-LCP1 Antikörper

Bindungsspezifität: C-Term

Verwendungszweck: LCP1 Antibody - C-terminal region

Sequenz: ILEEIGGGQK VNDDIIVNWV NETLREAKKS SSISSFKDPK ISTSLPVLDL

Homologie: Cow: 100%, Dog: 100%, Guinea Pig: 86%, Horse: 100%, Human: 100%, Mouse: 100%, Pig: 100%, Rabbit: 100%, Rat: 100%, Zebrafish: 86%

Produktmerkmale: This is a rabbit polyclonal antibody against LCP1. It was validated on Western Blot using a cell lysate as a positive control.

Aufreinigung: Affinity Purified

Immunogen: The immunogen is a synthetic peptide directed towards the C terminal region of human LCP1

Anwendungsinformationen

Applikationshinweise: Optimal working dilution should be determined by the investigator.

Kommentare:

We also sell a specific blocking peptide that can be used in combination with this antibody. You can find the blocking peptide under AAP54687-100UG

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Konzentration: 0.5 mg/mL

Buffer: Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handhabung: prevent freeze-thaw cycles

Lagerung: 4 °C,-20 °C

Informationen zur Lagerung: For short term use, store at 2-8C up to 1 week. For long term storage, store at -20 °C in small aliquots to prevent freeze-thaw cycles.

Details zu LCP1

Target: LCP1 (Lymphocyte Cytosolic Protein 1 (LCP1))

Andere Bezeichnung: LCP1

Hintergrund:

Background Information: Plastins are a family of actin-binding proteins that are conserved throughout eukaryote evolution and expressed in most tissues of higher eukaryotes. In humans, two ubiquitous plastin isoforms (L and T) have been identified. The L isoform is expressed only in hemopoietic cell lineages, while the T isoform has been found in all other normal cells of solid tissues that have replicative potential (fibroblasts, endothelial cells, epithelial cells, melanocytes, etc.). However, L-plastin has been found in many types of malignant human cells of non-hemopoietic origin suggesting that its expression is induced accompanying tumorigenesis in solid tissues.Plastins are a family of actin-binding proteins that are conserved throughout eukaryote evolution and expressed in most tissues of higher eukaryotes. In humans, two ubiquitous plastin isoforms (L and T) have been identified. Plastin 1 (otherwise known as Fimbrin) is a third distinct plastin isoform which is specifically expressed at high levels in the small intestine. The L isoform is expressed only in hemopoietic cell lineages, while the T isoform has been found in all other normal cells of solid tissues that have replicative potential (fibroblasts, endothelial cells, epithelial cells, melanocytes, etc.). However, L-plastin has been found in many types of malignant human cells of non-hemopoietic origin suggesting that its expression is induced accompanying tumorigenesis in solid tissues. Publication Note: This RefSeq record includes a subset of the publications that are available for this gene. Please see the Entrez Gene record to access additional publications.

Gene Name: Lymphocyte cytosolic protein 1 (L-plastin)

Alternative Symbols: LPL, CP64, PLS2, LC64P, HEL-S-37, L-PLASTIN

Protein Name: Plastin-2

Molekulargewicht: 70kDa

Gen-ID: 3936

NCBI Accession: NP_002289

UniProt: P13796