KPNA5 Antikörper (C-Term)

Produktnummer ABIN2785826

Dieses Kaninchen Polyklonal-Antikörper erkennt spezifisch KPNA5 in WB. Er zeigt eine Reaktivität gegenüber Human, Maus, Ratte, Rind (Kuh), Hund, Pferd, Kaninchen, Meerschweinchen, Schwein und Zebrafisch (Danio rerio).

Kurzübersicht für KPNA5 Antikörper (C-Term) (ABIN2785826)

Target: KPNA5 (Karyopherin alpha 5 (Importin alpha 6) (KPNA5))

Reaktivität: Human, Maus, Ratte, Rind (Kuh), Hund, Pferd, Kaninchen, Meerschweinchen, Schwein, Zebrafisch (Danio rerio)

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser KPNA5 Antikörper ist unkonjugiert

Applikation: Western Blotting (WB)

Produktdetails anti-KPNA5 Antikörper

Bindungsspezifität: C-Term

Sequenz: TVMDSKIVQV ALNGLENILR LGEQESKQNG IGINPYCALI EEAYGLDKIE

Homologie: Cow: 100%, Dog: 100%, Guinea Pig: 79%, Horse: 100%, Human: 100%, Mouse: 79%, Pig: 93%, Rabbit: 86%, Rat: 86%, Zebrafish: 93%

Produktmerkmale: This is a rabbit polyclonal antibody against KPNA5. It was validated on Western Blot using a cell lysate as a positive control.

Aufreinigung: Affinity Purified

Immunogen: The immunogen is a synthetic peptide directed towards the C terminal region of human KPNA5

Anwendungsinformationen

Applikationshinweise: Optimal working dilutions should be determined experimentally by the investigator.

Kommentare:

Antigen size: 539 AA

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Konzentration: Lot specific

Buffer: Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handhabung: Avoid repeated freeze-thaw cycles.

Lagerung: -20 °C

Informationen zur Lagerung: For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.

Details zu KPNA5

Target: KPNA5 (Karyopherin alpha 5 (Importin alpha 6) (KPNA5))

Andere Bezeichnung: KPNA5

Hintergrund: The transport of molecules between the nucleus and the cytoplasm in eukaryotic cells is mediated by the nuclear pore complex (NPC) which consists of 60-100 proteins and is probably 120 million daltons in molecular size. Small molecules (up to 70 kD) can pass through the nuclear pore by nonselective diffusion, larger molecules are transported by an active process. Most nuclear proteins contain short basic amino acid sequences known as nuclear localization signals (NLSs). KPNA5 protein belongs to the importin alpha protein family and is thought to be involved in NLS-dependent protein import into the nucleus.The transport of molecules between the nucleus and the cytoplasm in eukaryotic cells is mediated by the nuclear pore complex (NPC) which consists of 60-100 proteins and is probably 120 million daltons in molecular size. Small molecules (up to 70 kD) can pass through the nuclear pore by nonselective diffusion, larger molecules are transported by an active process. Most nuclear proteins contain short basic amino acid sequences known as nuclear localization signals (NLSs). KPNA5 protein belongs to the importin alpha protein family and is thought to be involved in NLS-dependent protein import into the nucleus. Publication Note: This RefSeq record includes a subset of the publications that are available for this gene. Please see the Entrez Gene record to access additional publications.
Alias Symbols: IPOA6, SRP6
Protein Interaction Partner: SPOPL, NUP50, ANP32B, IL32, UBC, KPNB1, ANP32A, BRMS1, CUL3, MEPCE, CDKN1B,
Protein Size: 539

Molekulargewicht: 61 kDa

Gen-ID: 3841

NCBI Accession: NM_002269, NP_002260

UniProt: O15131

Pathways: Protein targeting to Nucleus