Fibromodulin Antikörper (N-Term)

Produktnummer ABIN2785800

Dieser Kaninchen Polyklonal Antikörper erkennt spezifisch Fibromodulin in WB. Er zeigt eine Reaktivität gegenüber Human, Ratte, Maus, Meerschweinchen, Pferd, Rind (Kuh), Hund und Kaninchen.

Kurzübersicht für Fibromodulin Antikörper (N-Term) (ABIN2785800)

Target: Fibromodulin (FMOD)

Reaktivität: Human, Ratte, Maus, Meerschweinchen, Pferd, Rind (Kuh), Hund, Kaninchen

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser Fibromodulin Antikörper ist unkonjugiert

Applikation: Western Blotting (WB)

Produktdetails anti-Fibromodulin Antikörper

Bindungsspezifität: N-Term

Sequenz: VYFQNNQITS IQEGVFDNAT GLLWIALHGN QITSDKVGRK VFSKLRHLER

Homologie: Cow: 93%, Dog: 93%, Guinea Pig: 100%, Horse: 100%, Human: 100%, Mouse: 100%, Rabbit: 93%, Rat: 100%

Produktmerkmale: This is a rabbit polyclonal antibody against FMOD. It was validated on Western Blot using a cell lysate as a positive control.

Aufreinigung: Affinity Purified

Immunogen: The immunogen is a synthetic peptide directed towards the N terminal region of human FMOD

Anwendungsinformationen

Applikationshinweise: Optimal working dilutions should be determined experimentally by the investigator.

Kommentare:

Antigen size: 376 AA

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Konzentration: Lot specific

Buffer: Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handhabung: Avoid repeated freeze-thaw cycles.

Lagerung: -20 °C

Informationen zur Lagerung: For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.

Details zu Fibromodulin

Target: Fibromodulin (FMOD)

Andere Bezeichnung: FMOD

Hintergrund: Fibromodulin is a member of a family of small interstitial proteoglycans, containing a central region composed of leucine-rich repeats with 4 keratan sulfate chains flanked by disulfide-bonded terminal domains. It may participate in the assembly of the extracellular matrix as it interacts with type I and type II collagen fibrils and inhibits fibrillogenesis in vitro. It may also regulate TGF-beta activities by sequestering TGF-beta into the extracellular matrix.Fibromodulin is a member of a family of small interstitial proteoglycans, containing a central region composed of leucine-rich repeats with 4 keratan sulfate chains flanked by disulfide-bonded terminal domains. It may participate in the assembly of the extracellular matrix as it interacts with type I and type II collagen fibrils and inhibits fibrillogenesis in vitro. It may also regulate TGF-beta activities by sequestering TGF-beta into the extracellular matrix. Publication Note: This RefSeq record includes a subset of the publications that are available for this gene. Please see the Entrez Gene record to access additional publications.
Alias Symbols: SLRR2E
Protein Interaction Partner: BTBD1, ZBTB32, CUL3, Dlg4, TGFB3, TGFB2, TGFB1,
Protein Size: 376

Molekulargewicht: 43 kDa

Gen-ID: 2331

NCBI Accession: NM_002023, NP_002014

UniProt: Q06828

Pathways: Glycosaminoglycan Metabolic Process