FKBP3 Antikörper (C-Term)

Produktnummer ABIN2785798

Dieser Kaninchen Polyklonal Antikörper detektiert spezifisch FKBP3 in WB. Es zeigt Reaktivität gegenüber Proben von Human, Maus, Ratte, Rind (Kuh), Pferd, Kaninchen, Hund, Meerschweinchen und Zebrafisch (Danio rerio).

Kurzübersicht für FKBP3 Antikörper (C-Term) (ABIN2785798)

Target: FKBP3 (FK506 Binding Protein 3, 25kDa (FKBP3))

Reaktivität: Human, Maus, Ratte, Rind (Kuh), Pferd, Kaninchen, Hund, Meerschweinchen, Zebrafisch (Danio rerio)

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser FKBP3 Antikörper ist unkonjugiert

Applikation: Western Blotting (WB)

Produktdetails anti-FKBP3 Antikörper

Bindungsspezifität: C-Term

Verwendungszweck: FKBP3 Antibody - C-terminal region

Sequenz: EALLTMSKGE KARLEIEPEW AYGKKGQPDA KIPPNAKLTF EVELVDID

Homologie: Cow: 100%, Dog: 100%, Guinea Pig: 100%, Horse: 100%, Human: 100%, Mouse: 100%, Rabbit: 100%, Rat: 100%, Zebrafish: 93%

Produktmerkmale: This is a rabbit polyclonal antibody against FKBP3. It was validated on Western Blot using a cell lysate as a positive control.

Aufreinigung: Affinity Purified

Immunogen: The immunogen is a synthetic peptide directed towards the C terminal region of human FKBP3

Anwendungsinformationen

Applikationshinweise: Optimal working dilution should be determined by the investigator.

Kommentare:

We also sell a specific blocking peptide that can be used in combination with this antibody. You can find the blocking peptide under AAP54612-100UG

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Konzentration: 0.5 mg/mL

Buffer: Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handhabung: prevent freeze-thaw cycles

Lagerung: 4 °C,-20 °C

Informationen zur Lagerung: For short term use, store at 2-8C up to 1 week. For long term storage, store at -20 °C in small aliquots to prevent freeze-thaw cycles.

Details zu FKBP3

Target: FKBP3 (FK506 Binding Protein 3, 25kDa (FKBP3))

Andere Bezeichnung: FKBP3

Hintergrund:

Background Information: FKBP3 is a member of the immunophilin protein family, which play a role in immunoregulation and basic cellular processes involving protein folding and trafficking. FKBP3 is a cis-trans prolyl isomerase that binds the immunosuppressants FK506 and rapamycin, as well as histone deacetylases, the transcription factor YY1, casein kinase II, and nucleolin. It has a higher affinity for rapamycin than for FK506 and thus may be an important target molecule for immunosuppression by rapamycin.The protein encoded by this gene is a member of the immunophilin protein family, which play a role in immunoregulation and basic cellular processes involving protein folding and trafficking. This encoded protein is a cis-trans prolyl isomerase that binds the immunosuppressants FK506 and rapamycin. It has a higher affinity for rapamycin than for FK506 and thus may be an important target molecule for immunosuppression by rapamycin.

Gene Name: FK506 binding protein 3, 25 kDa

Alternative Symbols: FKBP-3, FKBP25, PPIase, FKBP-25

Protein Name: Peptidyl-prolyl cis-trans isomerase FKBP3

Molekulargewicht: 25kDa

Gen-ID: 2287

NCBI Accession: NP_002004

UniProt: Q00688