FKBP3 Antikörper (C-Term)

Produktnummer ABIN2785798

Dieses Kaninchen Polyklonal-Antikörper erkennt spezifisch FKBP3 in WB. Er zeigt eine Reaktivität gegenüber Human, Maus, Ratte, Rind (Kuh), Pferd, Kaninchen, Hund, Meerschweinchen und Zebrafisch (Danio rerio).

Kurzübersicht für FKBP3 Antikörper (C-Term) (ABIN2785798)

Target: FKBP3 (FK506 Binding Protein 3, 25kDa (FKBP3))

Reaktivität: Human, Maus, Ratte, Rind (Kuh), Pferd, Kaninchen, Hund, Meerschweinchen, Zebrafisch (Danio rerio)

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser FKBP3 Antikörper ist unkonjugiert

Applikation: Western Blotting (WB)

Produktdetails anti-FKBP3 Antikörper

Bindungsspezifität: C-Term

Sequenz: EALLTMSKGE KARLEIEPEW AYGKKGQPDA KIPPNAKLTF EVELVDID

Homologie: Cow: 100%, Dog: 100%, Guinea Pig: 100%, Horse: 100%, Human: 100%, Mouse: 100%, Rabbit: 100%, Rat: 100%, Zebrafish: 93%

Produktmerkmale: This is a rabbit polyclonal antibody against FKBP3. It was validated on Western Blot using a cell lysate as a positive control.

Aufreinigung: Affinity Purified

Immunogen: The immunogen is a synthetic peptide directed towards the C terminal region of human FKBP3

Anwendungsinformationen

Applikationshinweise: Optimal working dilutions should be determined experimentally by the investigator.

Kommentare:

Antigen size: 224 AA

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Konzentration: Lot specific

Buffer: Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handhabung: Avoid repeated freeze-thaw cycles.

Lagerung: -20 °C

Informationen zur Lagerung: For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.

Details zu FKBP3

Target: FKBP3 (FK506 Binding Protein 3, 25kDa (FKBP3))

Andere Bezeichnung: FKBP3

Hintergrund: FKBP3 is a member of the immunophilin protein family, which play a role in immunoregulation and basic cellular processes involving protein folding and trafficking. FKBP3 is a cis-trans prolyl isomerase that binds the immunosuppressants FK506 and rapamycin, as well as histone deacetylases, the transcription factor YY1, casein kinase II, and nucleolin. It has a higher affinity for rapamycin than for FK506 and thus may be an important target molecule for immunosuppression by rapamycin.The protein encoded by this gene is a member of the immunophilin protein family, which play a role in immunoregulation and basic cellular processes involving protein folding and trafficking. This encoded protein is a cis-trans prolyl isomerase that binds the immunosuppressants FK506 and rapamycin. It has a higher affinity for rapamycin than for FK506 and thus may be an important target molecule for immunosuppression by rapamycin.
Alias Symbols: FKBP-25, PPIase, FKBP-3, FKBP25
Protein Interaction Partner: UBC, EDC4, IGF2BP3, SYNCRIP, SEC16A, EIF2B2, EIF2B3, DYNLL1, RFC4, YBX1, NMT1, KRT18, ILF2, HNRNPU, HNRNPA2B1, DDX1, ABCF1, MAP1S, C14orf166, DIMT1, NELFB, SRPK1, FBXO25, BARD1, MYH10, PACSIN3, LRRFIP1, TIMELESS, Nedd4, NEDD4L, CALM1, HDAC2, HDAC1, YY1, C
Protein Size: 224

Molekulargewicht: 25 kDa

Gen-ID: 2287

NCBI Accession: NM_002013, NP_002004

UniProt: Q00688