ARF6 Antikörper (Middle Region)

Produktnummer ABIN2785790

Der Kaninchen Polyklonal Anti-ARF6-Antikörper wurde für WB und IHC validiert. Er ist geeignet, ARF6 in Proben von Human, Ratte, Maus, Zebrafisch (Danio rerio), Rind (Kuh), Meerschweinchen, Pferd, Kaninchen, Schaf und Hund zu detektieren. Es ist 1 Publikation verfügbar.

Kurzübersicht für ARF6 Antikörper (Middle Region) (ABIN2785790)

Target: ARF6 (ADP-Ribosylation Factor 6 (ARF6))

Reaktivität: Human, Ratte, Maus, Zebrafisch (Danio rerio), Rind (Kuh), Meerschweinchen, Pferd, Kaninchen, Schaf, Hund

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser ARF6 Antikörper ist unkonjugiert

Applikation: Western Blotting (WB), Immunohistochemistry (IHC)

Produktdetails anti-ARF6 Antikörper

Bindungsspezifität: Middle Region

Sequenz: REMRDAIILI FANKQDLPDA MKPHEIQEKL GLTRIRDRNW YVQPSCATSG

Homologie: Cow: 100%, Dog: 100%, Guinea Pig: 100%, Horse: 100%, Human: 100%, Mouse: 100%, Rabbit: 100%, Rat: 100%, Sheep: 100%, Zebrafish: 100%

Produktmerkmale: This is a rabbit polyclonal antibody against ARF6. It was validated on Western Blot using a cell lysate as a positive control.

Aufreinigung: Affinity Purified

Immunogen: The immunogen is a synthetic peptide directed towards the middle region of human ARF6

Anwendungsinformationen

Applikationshinweise: Optimal working dilutions should be determined experimentally by the investigator.

Kommentare:

Antigen size: 175 AA

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Konzentration: Lot specific

Buffer: Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handhabung: Avoid repeated freeze-thaw cycles.

Lagerung: -20 °C

Informationen zur Lagerung: For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.

Referenzen für anti-ARF6 Antikörper (ABIN2785790)

Tagliatti, Fadda, Falace, Benfenati, Fassio: "Arf6 regulates the cycling and the readily releasable pool of synaptic vesicles at hippocampal synapse." in: eLife, Vol. 5, (2016) (PubMed).

Details zu ARF6

Target: ARF6 (ADP-Ribosylation Factor 6 (ARF6))

Andere Bezeichnung: ARF6

Hintergrund: ARF6 is a member of the human ARF family, which is part of the RAS superfamily. They are small guanine nucleotide-binding proteins that stimulate the ADP-ribosyltransferase activity of cholera toxin and play a role in vesicular trafficking and as activators of phospholipase D. ARF6 is localized to the plasma membrane, and regulates vesicular trafficking, remodelling of membrane lipids, and signaling pathways that lead to actin remodeling. This gene encodes a member of the human ARF gene family, which is part of the RAS superfamily. The ARF genes encode small guanine nucleotide-binding proteins that stimulate the ADP-ribosyltransferase activity of cholera toxin and play a role in vesicular trafficking and as activators of phospholipase D. The product of this gene is localized to the plasma membrane, and regulates vesicular trafficking, remodelling of membrane lipids, and signaling pathways that lead to actin remodeling. A pseudogene of this gene is located on chromosome 7. Publication Note: This RefSeq record includes a subset of the publications that are available for this gene. Please see the Entrez Gene record to access additional publications.
Alias Symbols: DKFZp564M0264
Protein Interaction Partner: UBC, LSB5, GGA1, STAU1, EGFR, CYTH1, CYTH2, GNAQ, FN1, VCP, APP, RAB11FIP3, RAB11FIP4, RAB11FIP5, USP6, IKBKG, GGA3, ITSN1, ASAP1, FBXO8, MEPCE, RUVBL2, ASAP3, MPP5, ZNF709, EXOC5, ARFIP2, AP3D1, PIP5K1C, ASAP2, AP3B1, PIP5K1A, PLD1, AP1B1, EZR, CHRM3, CA
Protein Size: 175

Molekulargewicht: 20 kDa

Gen-ID: 382

NCBI Accession: NM_001663, NP_001654

UniProt: P62330

Pathways: Steroid Hormone Mediated Signaling Pathway, Regulation of Actin Filament Polymerization, SARS-CoV-2 Protein Interaktom