Pellino 3 Antikörper (N-Term)
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- Target Alle Pellino 3 (PELI3) Antikörper anzeigen
- Pellino 3 (PELI3) (Pellino E3 Ubiquitin Protein Ligase Family Member 3 (PELI3))
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Bindungsspezifität
- N-Term
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Reaktivität
- Human, Maus, Pferd, Schwein, Ratte, Kaninchen, Rind (Kuh), Meerschweinchen, Hund
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Wirt
- Kaninchen
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Klonalität
- Polyklonal
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Konjugat
- Dieser Pellino 3 Antikörper ist unkonjugiert
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Applikation
- Western Blotting (WB)
- Sequenz
- VLEGNPEVGS PRTSDLQHRG NKGSCVLSSP GEDAQPGEEP IKYGELIVLG
- Homologie
- Cow: 93%, Dog: 86%, Guinea Pig: 86%, Horse: 100%, Human: 100%, Mouse: 77%, Pig: 100%, Rabbit: 79%, Rat: 86%
- Produktmerkmale
- This is a rabbit polyclonal antibody against PELI3. It was validated on Western Blot using a cell lysate as a positive control.
- Aufreinigung
- Affinity Purified
- Immunogen
- The immunogen is a synthetic peptide directed towards the N terminal region of human PELI3
- Top Product
- Discover our top product PELI3 Primärantikörper
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- Applikationshinweise
- Optimal working dilutions should be determined experimentally by the investigator.
- Kommentare
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Antigen size: 445 AA
- Beschränkungen
- Nur für Forschungszwecke einsetzbar
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- Format
- Liquid
- Konzentration
- Lot specific
- Buffer
- Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.
- Konservierungsmittel
- Sodium azide
- Vorsichtsmaßnahmen
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- Handhabung
- Avoid repeated freeze-thaw cycles.
- Lagerung
- -20 °C
- Informationen zur Lagerung
- For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.
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- Target
- Pellino 3 (PELI3) (Pellino E3 Ubiquitin Protein Ligase Family Member 3 (PELI3))
- Andere Bezeichnung
- PELI3 (PELI3 Produkte)
- Hintergrund
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Toll-like receptors (TLRs) and IL1R (IL1R1) are part of the innate immune response aimed at mobilizing defense mechanisms in response in infection or injury. Pellino proteins, such as PELI3, are intermediate components in the signaling cascades initiated by TLRs and IL1R.Toll-like receptors (TLRs, see MIM 603030) and IL1R (IL1R1, MIM 147810) are part of the innate immune response aimed at mobilizing defense mechanisms in response in infection or injury. Pellino proteins, such as PELI3, are intermediate components in the signaling cascades initiated by TLRs and IL1R (Jensen and Whitehead, 2003 [PubMed 12874243]).[supplied by OMIM].
Alias Symbols: MGC35521
Protein Interaction Partner: RIPK2, UBE2V1, UBE2N, IRAK1, APP, TRAF6, MAP3K14, MAP3K7, IRAK4, UBC, IRAK2,
Protein Size: 445 - Molekulargewicht
- 48 kDa
- Gen-ID
- 246330
- NCBI Accession
- NM_001098510, NP_001091980
- Pathways
- Toll-Like Receptors Cascades
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