Pellino 3 Antikörper (N-Term)

Produktnummer ABIN2785760

Dieser Kaninchen Polyklonal Antikörper detektiert spezifisch Pellino 3 in WB. Es zeigt Reaktivität gegenüber Proben von Human, Maus, Ratte, Pferd, Schwein, Kaninchen, Rind (Kuh) und Meerschweinchen.

Kurzübersicht für Pellino 3 Antikörper (N-Term) (ABIN2785760)

Target: Pellino 3 (PELI3) (Pellino E3 Ubiquitin Protein Ligase Family Member 3 (PELI3))

Reaktivität: Human, Maus, Ratte, Pferd, Schwein, Kaninchen, Rind (Kuh), Meerschweinchen

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser Pellino 3 Antikörper ist unkonjugiert

Applikation: Western Blotting (WB)

Produktdetails anti-Pellino 3 Antikörper

Bindungsspezifität: N-Term

Verwendungszweck: PELI3 Antibody - N-terminal region

Sequenz: VLEGNPEVGS PRTSDLQHRG NKGSCVLSSP GEDAQPGEEP IKYGELIVLG

Homologie: Cow: 92%, Guinea Pig: 93%, Horse: 85%, Human: 100%, Mouse: 92%, Pig: 100%, Rabbit: 93%, Rat: 93%

Produktmerkmale: This is a rabbit polyclonal antibody against PELI3. It was validated on Western Blot using a cell lysate as a positive control.

Aufreinigung: Affinity Purified

Immunogen: The immunogen is a synthetic peptide directed towards the N terminal region of human PELI3

Anwendungsinformationen

Applikationshinweise: Optimal working dilution should be determined by the investigator.

Kommentare:

We also sell a specific blocking peptide that can be used in combination with this antibody. You can find the blocking peptide under AAP54532-100UG

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Konzentration: 0.5 mg/mL

Buffer: Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handhabung: prevent freeze-thaw cycles

Lagerung: 4 °C,-20 °C

Informationen zur Lagerung: For short term use, store at 2-8C up to 1 week. For long term storage, store at -20 °C in small aliquots to prevent freeze-thaw cycles.

Details zu Pellino 3

Target: Pellino 3 (PELI3) (Pellino E3 Ubiquitin Protein Ligase Family Member 3 (PELI3))

Andere Bezeichnung: PELI3

Hintergrund:

Background Information: Toll-like receptors (TLRs) and IL1R (IL1R1) are part of the innate immune response aimed at mobilizing defense mechanisms in response in infection or injury. Pellino proteins, such as PELI3, are intermediate components in the signaling cascades initiated by TLRs and IL1R.Toll-like receptors (TLRs, see MIM 603030) and IL1R (IL1R1, MIM 147810) are part of the innate immune response aimed at mobilizing defense mechanisms in response in infection or injury. Pellino proteins, such as PELI3, are intermediate components in the signaling cascades initiated by TLRs and IL1R (Jensen and Whitehead, 2003 [PubMed 12874243]).[supplied by OMIM].

Gene Name: Pellino E3 ubiquitin protein ligase family member 3

Alternative Symbols: MGC35521

Protein Name: E3 ubiquitin-protein ligase pellino homolog 3

Molekulargewicht: 48kDa

Gen-ID: 246330

NCBI Accession: NP_001091980

UniProt: Q8N2H9

Pathways: Toll-Like Receptors Cascades