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LCK Antikörper (N-Term)
LCK
Reaktivität: Human, Maus, Ratte, Rind (Kuh), Schwein, Schaf, Hund, Pferd, Kaninchen, Meerschweinchen
WB
Wirt: Kaninchen
Polyclonal
unconjugated
Produktnummer ABIN2785754
Produktdetails anti-LCK Antikörper
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Target
Alle LCK Antikörper anzeigen
LCK
(Lymphocyte-Specific Protein tyrosine Kinase (LCK))
Bindungsspezifität
Alle Epitope für LCK Antikörper
N-Term
Reaktivität
Alle Reaktivitäten für LCK Antikörper
Human, Maus, Ratte, Rind (Kuh), Schwein, Schaf, Hund, Pferd, Kaninchen, Meerschweinchen
Wirt
Alle Wirte für LCK Antikörper
Kaninchen
Klonalität
Alle Klonalitäten für LCK Antikörper
Polyklonal
Konjugat
Alle Konjugate für LCK Antikörper
Dieser LCK Antikörper ist unkonjugiert
Applikation
Alle Applikationen für LCK Antikörper
Western Blotting (WB)
Sequenz
ENCHYPIVPL DGKGTLLIRN GSEVRDPLVT YEGSNPPASP LQDNLVIALH
Homologie
Cow: 100%, Dog: 100%, Guinea Pig: 86%, Horse: 100%, Human: 100%, Mouse: 93%, Pig: 100%, Rabbit: 100%, Rat: 93%, Sheep: 100%
Produktmerkmale
This is a rabbit polyclonal antibody against LCK. It was validated on Western Blot.
Aufreinigung
Affinity Purified
Immunogen
The immunogen is a synthetic peptide directed towards the N-terminal region of Human LCK
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Alternativen
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Anwendungsinformationen
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Applikationshinweise
Optimal working dilution should be determined by the investigator.
Beschränkungen
Nur für Forschungszwecke einsetzbar
Handhabung
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Format
Liquid
Konzentration
1 mg/mL
Buffer
Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.
Konservierungsmittel
Sodium azide
Vorsichtsmaßnahmen
This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
Handhabung
Avoid repeat freeze-thaw cycles.
Lagerung
-20 °C
Informationen zur Lagerung
For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.
Details zu LCK
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Target
LCK
(Lymphocyte-Specific Protein tyrosine Kinase (LCK))
Andere Bezeichnung
LCK (LCK Produkte )
Synonyme
zgc:136695 antikoerper, LCK antikoerper, Hck-3 antikoerper, Lsk antikoerper, Lskt antikoerper, p56 antikoerper, p56Lck antikoerper, LSK antikoerper, YT16 antikoerper, p56lck antikoerper, pp58lck antikoerper, P56LCK antikoerper, tkl antikoerper, Lck1 antikoerper, Lcktkr antikoerper, LCK proto-oncogene, Src family tyrosine kinase antikoerper, lymphocyte protein tyrosine kinase antikoerper, lck antikoerper, LCK antikoerper, Lck antikoerper
Hintergrund
LCK is a member of the Src family of protein tyrosine kinases (PTKs). It is a key signaling molecule in the selection and maturation of developing T-cells. It contains N-terminal sites for myristylation and palmitylation, a PTK domain, and SH2 and SH3 domains which are involved in mediating protein-protein interactions with phosphotyrosine-containing and proline-rich motifs, respectively. LCK localizes to the plasma membrane and pericentrosomal vesicles, and binds to cell surface receptors, including CD4 and CD8, and other signaling molecules. Protein Interaction Partner: LZTS2, CDKAL1, BAG6, UBC, WASL, WAS, env, SMAD3, SMAD2, MAPK1, HSP90AA1, Mbp, HAVCR2, PTPN22, G3BP1, nef, LAT, KHDRBS1, ADAM15, ZAP70, PAK2, LCK, CBL, SOCS3, SOCS2, SOCS1, IL2RB, CISH, YWHAQ, AJUBA, CD5, CBLB, SKAP1, SYK, SOS1, CD38, CD247, CD3E, FAM174A, Protein Size: 363
Molekulargewicht
39 kDa
Gen-ID
3932
Pathways
T-Zell Rezeptor Signalweg , Fc-epsilon Rezeptor Signalübertragung , EGFR Signaling Pathway , Neurotrophin Signalübertragung , Transition Metal Ion Homeostasis , Positive Regulation of Endopeptidase Activity , CXCR4-mediated Signaling Events , Thromboxane A2 Receptor Signaling
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