Fgr Antikörper (Middle Region)
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- Target Alle Fgr (FGR) Antikörper anzeigen
- Fgr (FGR) (Gardner-Rasheed Feline Sarcoma Viral (V-Fgr) Oncogene Homolog (FGR))
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Bindungsspezifität
- Middle Region
- Reaktivität
- Human, Maus, Ratte, Hund, Rind (Kuh), Meerschweinchen, Pferd, Kaninchen, Zebrafisch (Danio rerio)
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Wirt
- Kaninchen
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Klonalität
- Polyklonal
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Konjugat
- Dieser Fgr Antikörper ist unkonjugiert
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Applikation
- Western Blotting (WB)
- Sequenz
- CPPGCPASLY EAMEQTWRLD PEERPTFEYL QSFLEDYFTS AEPQYQPGDQ
- Homologie
- Cow: 86%, Dog: 93%, Guinea Pig: 83%, Horse: 93%, Human: 100%, Mouse: 93%, Rabbit: 92%, Rat: 93%, Zebrafish: 83%
- Produktmerkmale
- This is a rabbit polyclonal antibody against FGR. It was validated on Western Blot using a cell lysate as a positive control.
- Aufreinigung
- Affinity Purified
- Immunogen
- The immunogen is a synthetic peptide directed towards the middle region of human FGR
- Top Product
- Discover our top product FGR Primärantikörper
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- Applikationshinweise
- Optimal working dilutions should be determined experimentally by the investigator.
- Kommentare
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Antigen size: 529 AA
- Beschränkungen
- Nur für Forschungszwecke einsetzbar
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- Format
- Liquid
- Konzentration
- Lot specific
- Buffer
- Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.
- Konservierungsmittel
- Sodium azide
- Vorsichtsmaßnahmen
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- Handhabung
- Avoid repeated freeze-thaw cycles.
- Lagerung
- -20 °C
- Informationen zur Lagerung
- For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.
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- Target
- Fgr (FGR) (Gardner-Rasheed Feline Sarcoma Viral (V-Fgr) Oncogene Homolog (FGR))
- Andere Bezeichnung
- FGR (FGR Produkte)
- Synonyme
- SRC2 antikoerper, c-fgr antikoerper, c-src2 antikoerper, p55-Fgr antikoerper, p55c-fgr antikoerper, p58-Fgr antikoerper, p58c-fgr antikoerper, FGR proto-oncogene, Src family tyrosine kinase antikoerper, FGR antikoerper, Fgr antikoerper
- Hintergrund
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This gene is a member of the Src family of protein tyrosine kinases (PTKs). The encoded protein contains N-terminal sites for myristylation and palmitylation, a PTK domain, and SH2 and SH3 domains which are involved in mediating protein-protein interactions with phosphotyrosine-containing and proline-rich motifs, respectively. The protein localizes to plasma membrane ruffles, and functions as a negative regulator of cell migration and adhesion triggered by the beta-2 integrin signal transduction pathway. Infection with Epstein-Barr virus results in the overexpression of this gene. Multiple alternatively spliced variants, encoding the same protein, have been identified.
Alias Symbols: FLJ43153, MGC75096, SRC2, c-fgr, c-src2, p55c-fgr, p58c-fgr, p55-Fgr, p58-Fgr
Protein Interaction Partner: IKBKG, STAT3, HSP90AA1, ERBB2, NR1I2, UBC, DOK1, KHDRBS1, SYK, SH3KBP1, FASLG, INPP5D, SLAMF1, VDR, HCLS1, CCR3, DAB2, PTK2, CD24, WAS, SRC, CBL, FGR, SNCA, YWHAQ, CSK, ARRB1, NCOA6,
Protein Size: 529 - Molekulargewicht
- 59 kDa
- Gen-ID
- 2268
- NCBI Accession
- NM_001042729, NP_001036194
- UniProt
- P09769
- Pathways
- Sensory Perception of Sound, Stem Cell Maintenance, Regulation of Leukocyte Mediated Immunity, Positive Regulation of Immune Effector Process, CXCR4-mediated Signaling Events, Thromboxane A2 Receptor Signaling
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