CENPP Antikörper (N-Term)

Produktnummer ABIN2785700

Dieser Kaninchen Polyklonal Antikörper detektiert spezifisch CENPP in WB. Es zeigt Reaktivität gegenüber Proben von Human und Pferd.

Kurzübersicht für CENPP Antikörper (N-Term) (ABIN2785700)

Target: CENPP (Centromere Protein P (CENPP))

Reaktivität: Human, Pferd

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser CENPP Antikörper ist unkonjugiert

Applikation: Western Blotting (WB)

Produktdetails anti-CENPP Antikörper

Bindungsspezifität: N-Term

Verwendungszweck: CENPP Antibody - N-terminal region

Sequenz: VQKSFQAIHQ FNLEGWKSSK DLKNQLGHLE SELSFLSTLT GINIRNHSKQ

Homologie: Horse: 77%, Human: 100%

Produktmerkmale: This is a rabbit polyclonal antibody against CENPP. It was validated on Western Blot using a cell lysate as a positive control.

Aufreinigung: Affinity Purified

Immunogen: The immunogen is a synthetic peptide directed towards the N terminal region of human CENPP

Anwendungsinformationen

Applikationshinweise: Optimal working dilution should be determined by the investigator.

Kommentare:

We also sell a specific blocking peptide that can be used in combination with this antibody. You can find the blocking peptide under AAP54412-100UG

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Konzentration: 0.5 mg/mL

Buffer: Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handhabung: prevent freeze-thaw cycles

Lagerung: 4 °C,-20 °C

Informationen zur Lagerung: For short term use, store at 2-8C up to 1 week. For long term storage, store at -20 °C in small aliquots to prevent freeze-thaw cycles.

Details zu CENPP

Target: CENPP (Centromere Protein P (CENPP))

Andere Bezeichnung: CENPP

Hintergrund:

Background Information: CENPP is the component of the CENPA-CAD (nucleosome distal) complex, a complex recruited to centromeres which is involved in assembly of kinetochore proteins, mitotic progression and chromosome segregation. CENPP may be involved in incorporation of newly synthesized CENPA into centromeres via its interaction with the CENPA-NAC complex.CENPP is a subunit of a CENPH (MIM 605607)-CENPI (MIM 300065)-associated centromeric complex that targets CENPA (MIM 117139) to centromeres and is required for proper kinetochore function and mitotic progression (Okada et al., 2006 [PubMed 16622420]).[supplied by OMIM]. PRIMARYREFSEQ_SPAN PRIMARY_IDENTIFIER PRIMARY_SPAN COMP 1-1104 CR592049.1 1-1104 1105-1633 BC071726.1 622-1150 1634-1689 BX537851.1 972-1027 1690-3411 AK091247.1 839-2560 3412-3428 AL833701.1 3078-3094

Gene Name: Centromere protein P

Alternative Symbols: CENP-P

Protein Name: Centromere protein P

Molekulargewicht: 33kDa

Gen-ID: 401541

NCBI Accession: NP_001012267

UniProt: Q6IPU0