CENPP Antikörper (N-Term)

Produktnummer ABIN2785700

Dieses Kaninchen Polyklonal-Antikörper erkennt spezifisch CENPP in WB. Er zeigt eine Reaktivität gegenüber Human und Pferd.

Kurzübersicht für CENPP Antikörper (N-Term) (ABIN2785700)

Target: CENPP (Centromere Protein P (CENPP))

Reaktivität: Human, Pferd

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser CENPP Antikörper ist unkonjugiert

Applikation: Western Blotting (WB)

Produktdetails anti-CENPP Antikörper

Bindungsspezifität: N-Term

Sequenz: VQKSFQAIHQ FNLEGWKSSK DLKNQLGHLE SELSFLSTLT GINIRNHSKQ

Homologie: Horse: 77%, Human: 100%

Produktmerkmale: This is a rabbit polyclonal antibody against CENPP. It was validated on Western Blot using a cell lysate as a positive control.

Aufreinigung: Affinity Purified

Immunogen: The immunogen is a synthetic peptide directed towards the N terminal region of human CENPP

Anwendungsinformationen

Applikationshinweise: Optimal working dilutions should be determined experimentally by the investigator.

Kommentare:

Antigen size: 288 AA

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Konzentration: Lot specific

Buffer: Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handhabung: Avoid repeated freeze-thaw cycles.

Lagerung: -20 °C

Informationen zur Lagerung: For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.

Details zu CENPP

Target: CENPP (Centromere Protein P (CENPP))

Andere Bezeichnung: CENPP

Hintergrund: CENPP is the component of the CENPA-CAD (nucleosome distal) complex, a complex recruited to centromeres which is involved in assembly of kinetochore proteins, mitotic progression and chromosome segregation. CENPP may be involved in incorporation of newly synthesized CENPA into centromeres via its interaction with the CENPA-NAC complex.CENPP is a subunit of a CENPH (MIM 605607)-CENPI (MIM 300065)-associated centromeric complex that targets CENPA (MIM 117139) to centromeres and is required for proper kinetochore function and mitotic progression (Okada et al., 2006 [PubMed 16622420]).[supplied by OMIM]. PRIMARYREFSEQ_SPAN PRIMARY_IDENTIFIER PRIMARY_SPAN COMP 1-1104 CR592049.1 1-1104 1105-1633 BC071726.1 622-1150 1634-1689 BX537851.1 972-1027 1690-3411 AK091247.1 839-2560 3412-3428 AL833701.1 3078-3094
Alias Symbols: CENP-P, FLJ33928, RP11-19J3.3
Protein Interaction Partner: KLC3, ZNF341, USHBP1, CCDC33, CENPO, TEX11, RPIA, NHLH1, GOLGA2, CENPU, CENPM, CENPN, CENPH, CENPQ, ITGB3BP, CENPI, UBC,
Protein Size: 288

Molekulargewicht: 33 kDa

Gen-ID: 401541

NCBI Accession: NM_001012267, NP_001012267

UniProt: Q6IPU0