MAGEA4 Antikörper (C-Term)

Produktnummer ABIN2785699

Produktdetails anti-MAGEA4 Antikörper

Target: MAGEA4 (Melanoma Antigen Family A, 4 (MAGEA4))

Bindungsspezifität: C-Term

Reaktivität: Human, Ratte, Maus, Rind (Kuh), Hund, Meerschweinchen, Pferd, Schwein, Kaninchen

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser MAGEA4 Antikörper ist unkonjugiert

Applikation: Western Blotting (WB)

Sequenz: ENYLEYRQVP GSNPARYEFL WGPRALAETS YVKVLEHVVR VNARVRIAYP

Homologie: Cow: 93%, Dog: 93%, Guinea Pig: 86%, Horse: 86%, Human: 100%, Mouse: 79%, Pig: 93%, Rabbit: 79%, Rat: 86%

Produktmerkmale: This is a rabbit polyclonal antibody against MAGEA4. It was validated on Western Blot using a cell lysate as a positive control.

Aufreinigung: Affinity Purified

Immunogen: The immunogen is a synthetic peptide directed towards the C terminal region of human MAGEA4

Anwendungsinformationen

Applikationshinweise: Optimal working dilutions should be determined experimentally by the investigator.

Kommentare:

Antigen size: 317 AA

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Konzentration: Lot specific

Buffer: Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handhabung: Avoid repeated freeze-thaw cycles.

Lagerung: -20 °C

Informationen zur Lagerung: For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.

Details zu MAGEA4

Target: MAGEA4 (Melanoma Antigen Family A, 4 (MAGEA4))

Andere Bezeichnung: MAGEA4 (MAGEA4 Produkte)

Hintergrund: MAGEA4 is a member of the MAGEA family. The members of this family are proteins with 50 to 80 % sequence identity to each other. The promoters and first exons of the MAGEA genes show considerable variability, suggesting that the existence of this gene family enables the same function to be expressed under different transcriptional controls. The MAGEA genes are clustered at chromosomal location Xq28. They have been implicated in some hereditary disorders, such as dyskeratosis congenita.This gene is a member of the MAGEA gene family. The members of this family encode proteins with 50 to 80 % sequence identity to each other. The promoters and first exons of the MAGEA genes show considerable variability, suggesting that the existence of this gene family enables the same function to be expressed under different transcriptional controls. The MAGEA genes are clustered at chromosomal location Xq28. They have been implicated in some hereditary disorders, such as dyskeratosis congenita. At least four variants encoding the same protein have been found for this gene.
Alias Symbols: MAGE-41, MAGE-X2, MAGE4, MAGE4A, MAGE4B, MGC21336, CT1.4
Protein Interaction Partner: AMOTL2, WBP2, UQCRB, TK1, GTF3C1, TEKT4, TRIM69, TIGD5, BEX2, UBXN6, AMOT, ARNT2, UBC, APP, HLA-A, PIAS2, PSMD10, POT1,
Protein Size: 317

Molekulargewicht: 35 kDa

Gen-ID: 4103

NCBI Accession: NM_001011548, NP_001011548

UniProt: P43358