IMPDH1 Antikörper (C-Term)

Produktnummer ABIN2785672

Dieser Kaninchen Polyklonal Antikörper detektiert spezifisch IMPDH1 in WB. Es zeigt Reaktivität gegenüber Proben von Human, Maus, Ratte, Rind (Kuh), Hund, Meerschweinchen, Pferd, Zebrafisch (Danio rerio), Kaninchen und Saccharomyces cerevisiae.

Kurzübersicht für IMPDH1 Antikörper (C-Term) (ABIN2785672)

Target: IMPDH1 (Inosine 5'-Phosphate Dehydrogenase 1 (IMPDH1))

Reaktivität: Human, Maus, Ratte, Rind (Kuh), Hund, Meerschweinchen, Pferd, Zebrafisch (Danio rerio), Kaninchen, Saccharomyces cerevisiae

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser IMPDH1 Antikörper ist unkonjugiert

Applikation: Western Blotting (WB)

Produktdetails anti-IMPDH1 Antikörper

Bindungsspezifität: C-Term

Verwendungszweck: IMPDH1 Antibody - C-terminal region

Sequenz: DGVRLKKYRG MGSLDAMEKS SSSQKRYFSE GDKVKIAQGV SGSIQDKGSI

Homologie: Cow: 100%, Dog: 100%, Guinea Pig: 100%, Horse: 100%, Human: 100%, Mouse: 100%, Rabbit: 100%, Rat: 100%, Yeast: 100%, Zebrafish: 100%

Produktmerkmale: This is a rabbit polyclonal antibody against IMPDH1. It was validated on Western Blot.

Aufreinigung: Affinity Purified

Immunogen: The immunogen is a synthetic peptide directed towards the C-terminal region of IMPDH1

Anwendungsinformationen

Applikationshinweise: Optimal working dilution should be determined by the investigator.

Kommentare:

We also sell a specific blocking peptide that can be used in combination with this antibody. You can find the blocking peptide under AAP54364-100UG

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Konzentration: 0.5 mg/mL

Buffer: Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handhabung: prevent freeze-thaw cycles

Lagerung: 4 °C,-20 °C

Informationen zur Lagerung: For short term use, store at 2-8C up to 1 week. For long term storage, store at -20 °C in small aliquots to prevent freeze-thaw cycles.

Details zu IMPDH1

Target: IMPDH1 (Inosine 5'-Phosphate Dehydrogenase 1 (IMPDH1))

Andere Bezeichnung: IMPDH1

Hintergrund:

Background Information: The protein encoded by this gene acts as a homotetramer to regulate cell growth. The encoded protein is an enzyme that catalyzes the synthesis of xanthine monophosphate (XMP) from inosine-5'-monophosphate (IMP). This is the rate-limiting step in the de novo synthesis of guanine nucleotides. Defects in this gene are a cause of retinitis pigmentosa type 10 (RP10). Several transcript variants encoding different isoforms have been found for this gene.

Alternative Symbols: IMPD, RP10, IMPD1, LCA11, IMPDH-I, sWSS2608

Protein Name: Inosine-5'-monophosphate dehydrogenase 1

Molekulargewicht: 63kDa

Gen-ID: 3614

NCBI Accession: NP_001096075

UniProt: P20839

Pathways: Ribonucleoside Biosynthetic Process