IMPDH1 Antikörper (Middle Region)

Produktnummer ABIN2785671

Produktdetails anti-IMPDH1 Antikörper

Target: IMPDH1 (Inosine 5'-Phosphate Dehydrogenase 1 (IMPDH1))

Bindungsspezifität: Middle Region

Reaktivität: Human, Maus, Ratte, Rind (Kuh), Hund, Meerschweinchen, Pferd, Zebrafisch (Danio rerio), Kaninchen, Saccharomyces cerevisiae

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser IMPDH1 Antikörper ist unkonjugiert

Applikation: Western Blotting (WB), Immunohistochemistry (IHC)

Sequenz: KKGKLPIVND CDELVAIIAR TDLKKNRDYP LASKDSQKQL LCGAAVGTRE

Homologie: Cow: 100%, Dog: 100%, Guinea Pig: 100%, Horse: 100%, Human: 100%, Mouse: 100%, Rabbit: 100%, Rat: 100%, Yeast: 79%, Zebrafish: 100%

Produktmerkmale: This is a rabbit polyclonal antibody against IMPDH1. It was validated on Western Blot using a cell lysate as a positive control.

Aufreinigung: Affinity Purified

Immunogen: The immunogen is a synthetic peptide directed towards the middle region of human IMPDH1

Anwendungsinformationen

Applikationshinweise: Optimal working dilutions should be determined experimentally by the investigator.

Kommentare:

Antigen size: 563 AA

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Konzentration: Lot specific

Buffer: Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handhabung: Avoid repeated freeze-thaw cycles.

Lagerung: -20 °C

Informationen zur Lagerung: For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.

Details zu IMPDH1

Target: IMPDH1 (Inosine 5'-Phosphate Dehydrogenase 1 (IMPDH1))

Andere Bezeichnung: IMPDH1 (IMPDH1 Produkte)

Synonyme: IMPD antikoerper, IMPD1 antikoerper, LCA11 antikoerper, RP10 antikoerper, sWSS2608 antikoerper, B930086D20Rik antikoerper, IMPD 1 antikoerper, IMPDH 1 antikoerper, D3 antikoerper, IMPD 1b antikoerper, IMPDH 1b antikoerper, IMPDH1 antikoerper, id:ibd5035 antikoerper, si:dkey-31f5.7 antikoerper, wu:fa09h11 antikoerper, wu:fa99c03 antikoerper, zgc:113446 antikoerper, imp antikoerper, imp1 antikoerper, imp2 antikoerper, IMPD 1a antikoerper, IMPDH 1a antikoerper, zgc:91911 antikoerper, inosine monophosphate dehydrogenase 1 antikoerper, inosine-5'-monophosphate dehydrogenase 1 antikoerper, IMP (inosine 5'-monophosphate) dehydrogenase 1b antikoerper, IMP (inosine 5'-monophosphate) dehydrogenase 1 antikoerper, IMP (inosine 5'-monophosphate) dehydrogenase 1a antikoerper, IMPDH1 antikoerper, Impdh1 antikoerper, LOC100442769 antikoerper, impdh1 antikoerper, impdh1b antikoerper, impdh1.L antikoerper, impdh1a antikoerper

Hintergrund: IMPDH1 acts as a homotetramer to regulate cell growth. It is an enzyme that catalyzes the synthesis of xanthine monophosphate (XMP) from inosine-5'-monophosphate (IMP). This is the rate-limiting step in the de novo synthesis of guanine nucleotides. Defects in this gene are a cause of retinitis pigmentosa type 10 (RP10).
Alias Symbols: DKFZp781N0678, IMPD, IMPD1, LCA11, RP10, sWSS2608
Protein Interaction Partner: UBC, LAMP2, IMPDH2, XRCC6, GMNN, HTRA1, DDX3X, SUMO4,
Protein Size: 563

Molekulargewicht: 62 kDa

Gen-ID: 3614

NCBI Accession: NM_183243, NP_899066

UniProt: P20839

Pathways: Ribonucleoside Biosynthetic Process