Glutathione Reductase Antikörper (N-Term)

Produktnummer ABIN2785662

Produktdetails anti-Glutathione Reductase Antikörper

Target: Glutathione Reductase (GSR)

Bindungsspezifität: N-Term

Reaktivität: Human, Ratte, Maus, Kaninchen, Meerschweinchen, Rind (Kuh), Hund, Pferd

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser Glutathione Reductase Antikörper ist unkonjugiert

Applikation: Western Blotting (WB), Immunohistochemistry (IHC)

Sequenz: PTIEVSGKKY TAPHILIATG GMPSTPHESQ IPGASLGITS DGFFQLEELP

Homologie: Cow: 93%, Dog: 93%, Guinea Pig: 100%, Horse: 86%, Human: 100%, Mouse: 100%, Rabbit: 100%, Rat: 93%

Produktmerkmale: This is a rabbit polyclonal antibody against GSR. It was validated on Western Blot using a cell lysate as a positive control.

Aufreinigung: Affinity Purified

Immunogen: The immunogen is a synthetic peptide directed towards the N terminal region of human GSR

Anwendungsinformationen

Applikationshinweise: Optimal working dilutions should be determined experimentally by the investigator.

Kommentare:

Antigen size: 522 AA

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Konzentration: Lot specific

Buffer: Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handhabung: Avoid repeated freeze-thaw cycles.

Lagerung: -20 °C

Informationen zur Lagerung: For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.

Referenzen für anti-Glutathione Reductase Antikörper (ABIN2785662)

Hoffmann, Dietrich, Herrmann, Schacht, Albrecht, Methner: "Dimethyl Fumarate Induces Glutathione Recycling by Upregulation of Glutathione Reductase." in: Oxidative medicine and cellular longevity, Vol. 2017, pp. 6093903, (2017) (PubMed).

Details zu Glutathione Reductase

Target: Glutathione Reductase (GSR)

Andere Bezeichnung: GSR (GSR Produkte)

Synonyme: GR antikoerper, ATGR2 antikoerper, EMB2360 antikoerper, glutathione reductase antikoerper, AI325518 antikoerper, D8Ertd238e antikoerper, Gr-1 antikoerper, Gr1 antikoerper, DDBDRAFT_0168952 antikoerper, DDBDRAFT_0231410 antikoerper, DDB_0168952 antikoerper, DDB_0231410 antikoerper, 2151 antikoerper, CG2151 antikoerper, DTR antikoerper, Dm-TrxR antikoerper, DmTR antikoerper, DmTrx antikoerper, DmTrxR antikoerper, DmTrxR-1 antikoerper, Dmel\\CG2151 antikoerper, Gr antikoerper, Trx antikoerper, TrxR antikoerper, TrxR-1 antikoerper, Trxr1 antikoerper, anon-WO03040301.185 antikoerper, anon-WO03040301.187 antikoerper, dTrxR antikoerper, dmtrxr-1 antikoerper, gr antikoerper, l(1)G0154 antikoerper, l(1)G0379 antikoerper, l(1)G0477 antikoerper, l(1)G0481 antikoerper, trxr-1 antikoerper, gor1 antikoerper, glutathione reductase, gro-2 antikoerper, glutathione reductase antikoerper, glutathione-disulfide reductase antikoerper, GR; GRase antikoerper, mitochondrial glutathione reductase Pgr1 antikoerper, Glutathione reductase (GR) (GRase) antikoerper, Thioredoxin reductase-1 antikoerper, glutathione-disulfide reductase family protein antikoerper, glutathione reductase 1 antikoerper, GR antikoerper, gor antikoerper, GSR antikoerper, GSR1 antikoerper, Gsr_2 antikoerper, Gsr antikoerper, GSHR1 antikoerper, gsr antikoerper, LbGR antikoerper, pgr1 antikoerper, GSHR2 antikoerper, GLR2 antikoerper, Bcen_2392 antikoerper, RPE_1989 antikoerper, HCAG_02219 antikoerper, SJAG_01162 antikoerper, Trxr-1 antikoerper, PF14_0192 antikoerper, POPTR_0001s14480g antikoerper, gsr1 antikoerper

Hintergrund: GSR belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family. It maintains high levels of reduced glutathione in the cytosol. Both glutathione and glutathione reductase are inducible by D3T, and that upregulation of GSH biosynthesis underlies D3T-mediated cytoprotection against ROS/RNS-elicited injury to human vascular smooth muscle cells.
Alias Symbols: MGC78522
Protein Interaction Partner: SUMO1, CNDP2, GINS2, PROSC, AHSA1, NDRG1, DDX39A, NAMPT, KYNU, DDX39B, RPS6KA1, PEPD, MVD, LDHA, HSPD1, GBP2, EEF2, ADSS, C11orf49, UBC, FOLR1, ISG15, ELAVL1, SUMO4, PJA1, OCM, GSR,
Protein Size: 522

Molekulargewicht: 56 kDa

Gen-ID: 2936

NCBI Accession: NM_000637, NP_000628

UniProt: P00390

Pathways: Thyroid Hormone Synthesis, Cell RedoxHomeostasis