FUCA1 Antikörper (N-Term)

Produktnummer ABIN2785639

Produktdetails anti-FUCA1 Antikörper

Target: FUCA1 (Fucosidase, alpha-L- 1, Tissue (FUCA1))

Bindungsspezifität: N-Term

Reaktivität: Human, Maus, Ratte, Rind (Kuh), Hund, Kaninchen, Meerschweinchen, Pferd, Schwein

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser FUCA1 Antikörper ist unkonjugiert

Applikation: Western Blotting (WB)

Sequenz: PSPVSWNWNS KDVGPHRDLV GELGTALRKR NIRYGLYHSL LEWFHPLYLL

Homologie: Cow: 100%, Dog: 93%, Guinea Pig: 93%, Horse: 93%, Human: 100%, Mouse: 100%, Pig: 100%, Rabbit: 79%, Rat: 100%

Produktmerkmale: This is a rabbit polyclonal antibody against FUCA1. It was validated on Western Blot using a cell lysate as a positive control.

Aufreinigung: Affinity Purified

Immunogen: The immunogen is a synthetic peptide directed towards the N terminal region of human FUCA1

Anwendungsinformationen

Applikationshinweise: Optimal working dilutions should be determined experimentally by the investigator.

Kommentare:

Antigen size: 466 AA

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Konzentration: Lot specific

Buffer: Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handhabung: Avoid repeated freeze-thaw cycles.

Lagerung: -20 °C

Informationen zur Lagerung: For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.

Details zu FUCA1

Target: FUCA1 (Fucosidase, alpha-L- 1, Tissue (FUCA1))

Andere Bezeichnung: FUCA1 (FUCA1 Produkte)

Synonyme: FUCA antikoerper, FUCA1 antikoerper, 0610006A03Rik antikoerper, 9530055J05Rik antikoerper, Afuc antikoerper, Fuca antikoerper, fuca antikoerper, fuca1 antikoerper, ATFUC1 antikoerper, F24D13.11 antikoerper, F24D13_11 antikoerper, alpha-L-fucosidase 1 antikoerper, wu:fb02a09 antikoerper, zgc:101116 antikoerper, alpha-L-fucosidase 1 antikoerper, fucosidase, alpha-L- 1, tissue antikoerper, alpha-L-fucosidase 1 L homeolog antikoerper, alpha-L-fucosidase 1, tandem duplicate 2 antikoerper, FUCA1 antikoerper, Fuca1 antikoerper, fuca1.L antikoerper, fuca1 antikoerper, FUC1 antikoerper, LOC9317020 antikoerper, LOC100285202 antikoerper, fuca1.2 antikoerper

Hintergrund: Alpha-L-fucosidase (EC 3.2.1.51) is a lysosomal enzyme involved in the degradation of fucose-containing glycoproteins and glycolipids. At least 2 separate polymorphic alpha-L-fucosidases are recognized in man: that in tissues, FUCA1, which is deficient in fucosidosis, and that in plasma, FUCA2. Fucosidosis is an autosomal recessive lysosomal storage disease caused by defective alpha-L-fucosidase with accumulation of fucose in the tissues. Different phenotypes include clinical features such as neurologic deterioration, growth retardation, visceromegaly, and seizures in a severe early form, coarse facial features, angiokeratoma corporis diffusum, spasticity and delayed psychomotor development in a longer surviving form, and an unusual spondylometaphyseoepiphyseal dysplasia in yet another form.[supplied by OMIM]. Publication Note: This RefSeq record includes a subset of the publications that are available for this gene. Please see the Entrez Gene record to access additional publications.
Alias Symbols: FUCA
Protein Interaction Partner: PAXIP1, BARD1, APP, CUL3, VAV2, USP21, MARK2,
Protein Size: 466

Molekulargewicht: 54 kDa

Gen-ID: 2517

NCBI Accession: NM_000147, NP_000138

UniProt: P04066

Pathways: Glycosaminoglycan Metabolic Process