FTL Antikörper (Middle Region)

Produktnummer ABIN2785638

Der Kaninchen Polyklonal Anti-FTL-Antikörper wurde für WB und IHC validiert. Er ist geeignet, FTL in Proben von Human, Maus, Ratte, Pferd, Rind (Kuh), Hund, Schwein, Kaninchen, Meerschweinchen und Schaf zu detektieren.

Kurzübersicht für FTL Antikörper (Middle Region) (ABIN2785638)

Target: FTL (Ferritin, Light Polypeptide (FTL))

Reaktivität: Human, Maus, Ratte, Pferd, Rind (Kuh), Hund, Schwein, Kaninchen, Meerschweinchen, Schaf

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser FTL Antikörper ist unkonjugiert

Applikation: Western Blotting (WB), Immunohistochemistry (IHC)

Produktdetails anti-FTL Antikörper

Bindungsspezifität: Middle Region

Sequenz: ALLDLHALGS ARTDPHLCDF LETHFLDEEV KLIKKMGDHL TNLHRLGGPE

Homologie: Cow: 79%, Dog: 93%, Guinea Pig: 92%, Horse: 86%, Human: 100%, Mouse: 100%, Pig: 93%, Rabbit: 93%, Rat: 100%, Sheep: 77%

Produktmerkmale: This is a rabbit polyclonal antibody against FTL. It was validated on Western Blot using a cell lysate as a positive control.

Aufreinigung: Affinity Purified

Immunogen: The immunogen is a synthetic peptide directed towards the middle region of human FTL

Anwendungsinformationen

Applikationshinweise: Optimal working dilutions should be determined experimentally by the investigator.

Kommentare:

Antigen size: 175 AA

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Konzentration: Lot specific

Buffer: Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handhabung: Avoid repeated freeze-thaw cycles.

Lagerung: -20 °C

Informationen zur Lagerung: For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.

Details zu FTL

Target: FTL (Ferritin, Light Polypeptide (FTL))

Andere Bezeichnung: FTL

Hintergrund: FTL is the light subunit of the ferritin protein. Ferritin is the major intracellular iron storage protein in prokaryotes and eukaryotes. It is composed of 24 subunits of the heavy and light ferritin chains. Variation in ferritin subunit composition may affect the rates of iron uptake and release in different tissues. A major function of ferritin is the storage of iron in a soluble and nontoxic state. Defects in this light chain ferritin gene are associated with several neurodegenerative diseases and hyperferritinemia-cataract syndrome. This gene encodes the light subunit of the ferritin protein. Ferritin is the major intracellular iron storage protein in prokaryotes and eukaryotes. It is composed of 24 subunits of the heavy and light ferritin chains. Variation in ferritin subunit composition may affect the rates of iron uptake and release in different tissues. A major function of ferritin is the storage of iron in a soluble and nontoxic state. Defects in this light chain ferritin gene are associated with several neurodegenerative diseases and hyperferritinemia-cataract syndrome. This gene has multiple pseudogenes. Publication Note: This RefSeq record includes a subset of the publications that are available for this gene. Please see the Entrez Gene record to access additional publications.
Alias Symbols: MGC71996, NBIA3
Protein Interaction Partner: USHBP1, SDCBP, MYOG, KPNA3, FTL, FTH1, CEP250, CEP57, AURKA, PACSIN2, COL4A3BP, IGSF8, NAMPT, SMAD9, HTT, VKORC1, PPP1CC, POLR2D, HSPD1, HSP90AB3P, EIF4G1, TOX4, MYOC, UBC, CLEC4G, RAP2A, PIK3CA, GRB2, UCHL5, MPHOSPH6, TAF10, MPP6, IGDCC3, MAP3K12, KNG1,
Protein Size: 175

Molekulargewicht: 20 kDa

Gen-ID: 2512

NCBI Accession: NM_000146, NP_000137

UniProt: P02792

Pathways: Transition Metal Ion Homeostasis