ETFA Antikörper (Middle Region)

Produktnummer ABIN2785637

Dieses Anti-ETFA-Antikörper ist ein Kaninchen Polyklonal-Antikörper zur Detektion von ETFA in WB. Geeignet für Human, Maus, Ratte, Rind (Kuh), Hund, Meerschweinchen, Pferd, Kaninchen, Ziege, Saccharomyces cerevisiae und Zebrafisch (Danio rerio).

Kurzübersicht für ETFA Antikörper (Middle Region) (ABIN2785637)

Target: ETFA (Electron-Transfer-Flavoprotein, alpha Polypeptide (ETFA))

Reaktivität: Human, Maus, Ratte, Rind (Kuh), Hund, Meerschweinchen, Pferd, Kaninchen, Ziege, Saccharomyces cerevisiae, Zebrafisch (Danio rerio)

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser ETFA Antikörper ist unkonjugiert

Applikation: Western Blotting (WB)

Produktdetails anti-ETFA Antikörper

Bindungsspezifität: Middle Region

Sequenz: VVSGGRGLKS GENFKLLYDL ADQLHAAVGA SRAAVDAGFV PNDMQVGQTG

Homologie: Cow: 100%, Dog: 100%, Goat: 86%, Guinea Pig: 100%, Horse: 100%, Human: 100%, Mouse: 100%, Rabbit: 100%, Rat: 100%, Yeast: 92%, Zebrafish: 93%

Produktmerkmale: This is a rabbit polyclonal antibody against ETFA. It was validated on Western Blot using a cell lysate as a positive control.

Aufreinigung: Affinity Purified

Immunogen: The immunogen is a synthetic peptide directed towards the middle region of human ETFA

Anwendungsinformationen

Applikationshinweise: Optimal working dilutions should be determined experimentally by the investigator.

Kommentare:

Antigen size: 333 AA

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Konzentration: Lot specific

Buffer: Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handhabung: Avoid repeated freeze-thaw cycles.

Lagerung: -20 °C

Informationen zur Lagerung: For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.

Details zu ETFA

Target: ETFA (Electron-Transfer-Flavoprotein, alpha Polypeptide (ETFA))

Andere Bezeichnung: ETFA

Hintergrund: ETFA participates in catalyzing the initial step of the mitochondrial fatty acid beta-oxidation. It shuttles electrons between primary flavoprotein dehydrogenases and the membrane-bound electron transfer flavoprotein ubiquinone oxidoreductase. Defects in electron-transfer-flavoprotein have been implicated in type II glutaricaciduria in which multiple acyl-CoA dehydrogenase deficiencies result in large excretion of glutaric, lactic, ethylmalonic, butyric, isobutyric, 2-methyl-butyric, and isovaleric acids.ETFA participates in catalyzing the initial step of the mitochondrial fatty acid beta-oxidation. It shuttles electrons between primary flavoprotein dehydrogenases and the membrane-bound electron transfer flavoprotein ubiquinone oxidoreductase. Defects in electron-transfer-flavoprotein have been implicated in type II glutaricaciduria in which multiple acyl-CoA dehydrogenase deficiencies result in large excretion of glutaric, lactic, ethylmalonic, butyric, isobutyric, 2-methyl-butyric, and isovaleric acids. Two transcript variants encoding different isoforms have been found for this gene.
Alias Symbols: EMA, GA2, MADD
Protein Interaction Partner: SUMO2, MDM2, PSEN1, PPP6R3, BAG3, TPM1, UBC, SORD, HADHA, ETFB, CDC42, HDAC5, MYC, ICT1, UBA5, DDA1, ATG101,
Protein Size: 333

Molekulargewicht: 35 kDa

Gen-ID: 2108

NCBI Accession: NM_000126, NP_000117

UniProt: P13804

Pathways: SARS-CoV-2 Protein Interaktom