CRISP1 Antikörper (N-Term)

Produktnummer ABIN2785457

Dieses Kaninchen Polyklonal-Antikörper erkennt spezifisch CRISP1 in WB. Er zeigt eine Reaktivität gegenüber Human, Rind (Kuh), Ziege, Schwein, Kaninchen, Zebrafisch (Danio rerio) und Hund.

Kurzübersicht für CRISP1 Antikörper (N-Term) (ABIN2785457)

Target: CRISP1 (Cysteine-Rich Secretory Protein 1 (CRISP1))

Reaktivität: Human, Rind (Kuh), Ziege, Schwein, Kaninchen, Zebrafisch (Danio rerio), Hund

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser CRISP1 Antikörper ist unkonjugiert

Applikation: Western Blotting (WB)

Produktdetails anti-CRISP1 Antikörper

Bindungsspezifität: N-Term

Sequenz: LKMSWSEEAA QNARIFSKYC DMTESNPLER RLPNTFCGEN MHMTSYPVSW

Homologie: Cow: 85%, Dog: 85%, Goat: 85%, Human: 100%, Pig: 85%, Rabbit: 79%, Zebrafish: 100%

Produktmerkmale: This is a rabbit polyclonal antibody against CRISP1. It was validated on Western Blot using a cell lysate as a positive control.

Aufreinigung: Affinity Purified

Immunogen: The immunogen is a synthetic peptide directed towards the N terminal region of human CRISP1

Anwendungsinformationen

Applikationshinweise: Optimal working dilutions should be determined experimentally by the investigator.

Kommentare:

Antigen size: 249 AA

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Konzentration: Lot specific

Buffer: Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handhabung: Avoid repeated freeze-thaw cycles.

Lagerung: -20 °C

Informationen zur Lagerung: For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.

Details zu CRISP1

Target: CRISP1 (Cysteine-Rich Secretory Protein 1 (CRISP1))

Andere Bezeichnung: CRISP1

Hintergrund: Fertilization consists of a sequence of specific cell-cell interactions culminating in the fusion of the sperm and egg plasma membranes. Recognition, binding, and fusion occur through the interaction of complementary molecules that are localized to specific domains of the sperm and egg plasma membranes. In the sperm, the postacrosomal region or equatorial segment is involved in sperm-egg plasma membrane fusion. CRISP1 is a member of the cysteine-rich secretory protein (CRISP) family. It is expressed in the epididymis, is secreted into the epididymal lumen, and binds to the postacrosomal region of the sperm head where it plays a role at fertilization in sperm-egg fusion through complementary sites localized on the egg surface.Fertilization consists of a sequence of specific cell-cell interactions culminating in the fusion of the sperm and egg plasma membranes. Recognition, binding, and fusion occur through the interaction of complementary molecules that are localized to specific domains of the sperm and egg plasma membranes. In the sperm, the postacrosomal region or equatorial segment is involved in sperm-egg plasma membrane fusion. The protein encoded by this gene is a member of the cysteine-rich secretory protein (CRISP) family. This protein is expressed in the epididymis, is secreted into the epididymal lumen, and binds to the postacrosomal region of the sperm head where it plays a role at fertilization in sperm-egg fusion through complementary sites localized on the egg surface. Two isoforms are encoded by transcript variants of this gene.
Alias Symbols: AEGL1, ARP, CRISP-1, HSCRISP1D, HSCRISP1G, HUMARP
Protein Size: 249

Molekulargewicht: 27 kDa

Gen-ID: 167

NCBI Accession: NM_001131, NP_001122

UniProt: P54107