GRK4 Antikörper (Middle Region)

Produktnummer ABIN2785447

Dieser Kaninchen Polyklonal Antikörper detektiert spezifisch GRK4 in WB. Es zeigt Reaktivität gegenüber Proben von Human, Maus, Ratte, Rind (Kuh), Pferd, Zebrafisch (Danio rerio), Hund, Meerschweinchen und Kaninchen.

Kurzübersicht für GRK4 Antikörper (Middle Region) (ABIN2785447)

Target: GRK4 (G Protein-Coupled Receptor Kinase 4 (GRK4))

Reaktivität: Human, Maus, Ratte, Rind (Kuh), Pferd, Zebrafisch (Danio rerio), Hund, Meerschweinchen, Kaninchen

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser GRK4 Antikörper ist unkonjugiert

Applikation: Western Blotting (WB)

Produktdetails anti-GRK4 Antikörper

Bindungsspezifität: Middle Region

Verwendungszweck: GRK4 Antibody - middle region

Sequenz: QSRFVVSLAY AYETKDALCL VLTIMNGGDL KFHIYNLGNP GFDEQRAVFY

Homologie: Cow: 79%, Dog: 93%, Guinea Pig: 93%, Horse: 100%, Human: 100%, Mouse: 79%, Rabbit: 100%, Rat: 93%, Zebrafish: 86%

Produktmerkmale: This is a rabbit polyclonal antibody against GRK4. It was validated on Western Blot using a cell lysate as a positive control.

Aufreinigung: Affinity Purified

Immunogen: The immunogen is a synthetic peptide directed towards the middle region of human GRK4

Anwendungsinformationen

Applikationshinweise: Optimal working dilution should be determined by the investigator.

Kommentare:

We also sell a specific blocking peptide that can be used in combination with this antibody. You can find the blocking peptide under ABIN8101178

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Konzentration: 0.5 mg/mL

Buffer: Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handhabung: prevent freeze-thaw cycles

Lagerung: 4 °C,-20 °C

Informationen zur Lagerung: For short term use, store at 2-8C up to 1 week. For long term storage, store at -20 °C in small aliquots to prevent freeze-thaw cycles.

Details zu GRK4

Target: GRK4 (G Protein-Coupled Receptor Kinase 4 (GRK4))

Andere Bezeichnung: GRK4

Hintergrund:

Background Information: GRK4 is a member of the guanine nucleotide-binding protein (G protein)-coupled receptor kinase subfamily of the Ser/Thr protein kinase family. The protein phosphorylates the activated forms of G protein-coupled receptors thus initiating its deactivation. GRK4 has been linked to both genetic and acquired hypertension.This gene encodes a member of the guanine nucleotide-binding protein (G protein)-coupled receptor kinase subfamily of the Ser/Thr protein kinase family. The protein phosphorylates the activated forms of G protein-coupled receptors thus initiating its deactivation. This gene has been linked to both genetic and acquired hypertension.

Gene Name: G protein-coupled receptor kinase 4

Alternative Symbols: IT11, GPRK4, GRK4a, GPRK2L

Protein Name: G protein-coupled receptor kinase 4

Molekulargewicht: 59kDa

Gen-ID: 2868

NCBI Accession: NP_001004057

UniProt: P32298

Pathways: Myometrial Relaxation and Contraction, Regulation of G-Protein Coupled Receptor Protein Signaling