GRK4 Antikörper (Middle Region)

Produktnummer ABIN2785447

Produktdetails anti-GRK4 Antikörper

Target: GRK4 (G Protein-Coupled Receptor Kinase 4 (GRK4))

Bindungsspezifität: Middle Region

Reaktivität: Human, Maus, Ratte, Rind (Kuh), Pferd, Zebrafisch (Danio rerio), Hund, Meerschweinchen, Kaninchen

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser GRK4 Antikörper ist unkonjugiert

Applikation: Western Blotting (WB)

Sequenz: QSRFVVSLAY AYETKDALCL VLTIMNGGDL KFHIYNLGNP GFDEQRAVFY

Homologie: Cow: 79%, Dog: 93%, Guinea Pig: 93%, Horse: 100%, Human: 100%, Mouse: 79%, Rabbit: 100%, Rat: 93%, Zebrafish: 86%

Produktmerkmale: This is a rabbit polyclonal antibody against GRK4. It was validated on Western Blot using a cell lysate as a positive control.

Aufreinigung: Affinity Purified

Immunogen: The immunogen is a synthetic peptide directed towards the middle region of human GRK4

Anwendungsinformationen

Applikationshinweise: Optimal working dilutions should be determined experimentally by the investigator.

Kommentare:

Antigen size: 532 AA

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Konzentration: Lot specific

Buffer: Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handhabung: Avoid repeated freeze-thaw cycles.

Lagerung: -20 °C

Informationen zur Lagerung: For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.

Details zu GRK4

Target: GRK4 (G Protein-Coupled Receptor Kinase 4 (GRK4))

Andere Bezeichnung: GRK4 (GRK4 Produkte)

Synonyme: GPRK2L antikoerper, GPRK4 antikoerper, GRK4a antikoerper, IT11 antikoerper, A830025H08Rik antikoerper, GRK antikoerper, Gprk2l antikoerper, Gprk4 antikoerper, AMPK antikoerper, AMPKalpha antikoerper, CG3051 antikoerper, DmAMPK alpha antikoerper, Dmel\\CG3051 antikoerper, EG:132E8.2 antikoerper, FBgn0023169 antikoerper, Gprk-4 antikoerper, ampk antikoerper, ampkalpha antikoerper, dAMPKa antikoerper, dAMPKalpha antikoerper, snf1a antikoerper, gprk4 antikoerper, gprk4-a antikoerper, grk4 antikoerper, GRK4 antikoerper, gprk4-b antikoerper, zgc:153020 antikoerper, gprk2l antikoerper, grk4a antikoerper, it11 antikoerper, G protein-coupled receptor kinase 4 antikoerper, AMP-activated protein kinase alpha subunit antikoerper, G protein-coupled receptor kinase 4 L homeolog antikoerper, G protein-coupled receptor kinase 4 S homeolog antikoerper, GRK4 antikoerper, Grk4 antikoerper, AMPKalpha antikoerper, grk4.L antikoerper, grk4.S antikoerper, grk4 antikoerper, LOC100540688 antikoerper

Hintergrund: GRK4 is a member of the guanine nucleotide-binding protein (G protein)-coupled receptor kinase subfamily of the Ser/Thr protein kinase family. The protein phosphorylates the activated forms of G protein-coupled receptors thus initiating its deactivation. GRK4 has been linked to both genetic and acquired hypertension.This gene encodes a member of the guanine nucleotide-binding protein (G protein)-coupled receptor kinase subfamily of the Ser/Thr protein kinase family. The protein phosphorylates the activated forms of G protein-coupled receptors thus initiating its deactivation. This gene has been linked to both genetic and acquired hypertension.
Alias Symbols: GPRK2L, GPRK4, GRK4a, IT11
Protein Interaction Partner: HSP90AA1, UBC, NEDD4, IKBKG, FSHR, CALM1, BDKRB2,
Protein Size: 532

Molekulargewicht: 59 kDa

Gen-ID: 2868

NCBI Accession: NM_001004057, NP_001004057

UniProt: P32298

Pathways: Myometrial Relaxation and Contraction, Regulation of G-Protein Coupled Receptor Protein Signaling