AKR1C2 Antikörper (N-Term)

Produktnummer ABIN2785422

Der Kaninchen Polyklonal anti-AKR1C2 Antikörper wird verwendet zum Nachweis von AKR1C2 in Proben von Human, Maus, Ratte, Rind (Kuh), Pferd, Kaninchen, Hund, Meerschweinchen und Schaf. Er wurde validiert für WB.

Kurzübersicht für AKR1C2 Antikörper (N-Term) (ABIN2785422)

Target: AKR1C2 (Aldo-keto Reductase Family 1, Member C2 (AKR1C2))

Reaktivität: Human, Maus, Ratte, Rind (Kuh), Pferd, Kaninchen, Hund, Meerschweinchen, Schaf

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser AKR1C2 Antikörper ist unkonjugiert

Applikation: Western Blotting (WB)

Produktdetails anti-AKR1C2 Antikörper

Bindungsspezifität: N-Term

Verwendungszweck: AKR1C2 Antibody - N-terminal region

Sequenz: LEAVKLAIEA GFHHIDSAHV YNNEEQVGLA IRSKIADGSV KREDIFYTSK

Homologie: Cow: 93%, Dog: 93%, Guinea Pig: 93%, Horse: 93%, Human: 100%, Mouse: 93%, Rabbit: 93%, Rat: 93%, Sheep: 86%

Produktmerkmale: This is a rabbit polyclonal antibody against AKR1C2. It was validated on Western Blot using a cell lysate as a positive control.

Aufreinigung: Affinity Purified

Immunogen: The immunogen is a synthetic peptide directed towards the N terminal region of human AKR1C2

Anwendungsinformationen

Applikationshinweise: Optimal working dilution should be determined by the investigator.

Kommentare:

We also sell a specific blocking peptide that can be used in combination with this antibody. You can find the blocking peptide under AAP53506-100UG

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Konzentration: 0.5 mg/mL

Buffer: Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handhabung: prevent freeze-thaw cycles

Lagerung: 4 °C,-20 °C

Informationen zur Lagerung: For short term use, store at 2-8C up to 1 week. For long term storage, store at -20 °C in small aliquots to prevent freeze-thaw cycles.

Details zu AKR1C2

Target: AKR1C2 (Aldo-keto Reductase Family 1, Member C2 (AKR1C2))

Andere Bezeichnung: AKR1C2

Hintergrund:

Background Information: This gene encodes a member of the aldo/keto reductase superfamily, which consists of more than 40 known enzymes and proteins. These enzymes catalyze the conversion of aldehydes and ketones to their corresponding alcohols using NADH and/or NADPH as cofactors. The enzymes display overlapping but distinct substrate specificity. This enzyme binds bile acid with high affinity, and shows minimal 3-alpha-hydroxysteroid dehydrogenase activity. This gene shares high sequence identity with three other gene members and is clustered with those three genes at chromosome 10p15-p14.

Gene Name: Aldo-keto reductase family 1, member C2 (dihydrodiol dehydrogenase 2, bile acid binding protein, 3-alpha hydroxysteroid dehydrogenase, type III)

Alternative Symbols: DD, DD2, TDD, BABP, DD-2, DDH2, HBAB, HAKRD, MCDR2, SRXY8, DD/BABP, AKR1C-pseudo

Protein Name: Aldo-keto reductase family 1 member C2

Molekulargewicht: 37kDa

Gen-ID: 1646

NCBI Accession: NP_995317

UniProt: P52895

Pathways: Steroid Hormone Biosynthesis, C21-Steroid Hormone Metabolic Process