EIF5 Antikörper (N-Term)

Produktnummer ABIN406354

Produktdetails anti-EIF5 Antikörper

Target: EIF5 (Eukaryotic Translation Initiation Factor 5 (EIF5))

Bindungsspezifität: N-Term

Reaktivität: Human, Maus, Ratte, Rind (Kuh), Pferd, Hund, Meerschweinchen, Kaninchen, Zebrafisch (Danio rerio)

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser EIF5 Antikörper ist unkonjugiert

Applikation: Western Blotting (WB)

Sequenz: SVNVNRSVSD QFYRYKMPRL IAKVEGKGNG IKTVIVNMVD VAKALNRPPT

Homologie: Cow: 100%, Dog: 100%, Guinea Pig: 100%, Horse: 100%, Human: 100%, Mouse: 100%, Rabbit: 100%, Rat: 100%, Zebrafish: 100%

Produktmerkmale: This is a rabbit polyclonal antibody against EIF5. It was validated on Western Blot using a cell lysate as a positive control.

Aufreinigung: Affinity Purified

Immunogen: The immunogen is a synthetic peptide directed towards the N terminal region of human EIF5

Anwendungsinformationen

Applikationshinweise: Optimal working dilutions should be determined experimentally by the investigator.

Kommentare:

Antigen size: 431 AA

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Konzentration: Lot specific

Buffer: Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handhabung: Avoid repeated freeze-thaw cycles.

Lagerung: -20 °C

Informationen zur Lagerung: For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.

Details zu EIF5

Target: EIF5 (Eukaryotic Translation Initiation Factor 5 (EIF5))

Andere Bezeichnung: EIF5 (EIF5 Produkte)

Hintergrund: EIF5 catalyzes the hydrolysis of GTP bound to the 40S ribosomal initiation complex (40S.mRNA.Met-tRNA[F].eIF-2.GTP) with the subsequent joining of a 60S ribosomal subunit resulting in the release of eIF-2 and the guanine nucleotide. The subsequent joining of a 60S ribosomal subunit results in the formation of a functional 80S initiation complex (80S.mRNA.Met-tRNA[F]).
Alias Symbols: EIF-5A
Protein Interaction Partner: DUSP12, HUWE1, UBC, TUBB, UBFD1, SCLY, ISOC1, MAT2B, FERMT2, YWHAQ, STK24, YWHAZ, YWHAH, YWHAE, EIF4H, VCL, SNRPD1, PCYT2, PFAS, PDHB, PAFAH1B1, HSPA9, HNRNPK, GNAI3, GLA, G6PD, DFFA, TBCB, CAPNS1, ALDH7A1, LMNA, PUM1, NRGN, FN1, EIF3B, RPL29, APP, Nedd4,
Protein Size: 431

Molekulargewicht: 49 kDa

Gen-ID: 1983

NCBI Accession: NM_183004, NP_892116

UniProt: P55010