LCA5 Antikörper (N-Term)

Produktnummer ABIN2785382

Dieser Kaninchen Polyklonal Antikörper detektiert spezifisch LCA5 in WB. Es zeigt Reaktivität gegenüber Proben von Human, Maus, Ratte, Hund, Meerschweinchen, Pferd, Kaninchen und Rind (Kuh).Es wurde in 1 Publikation zitiert.

Kurzübersicht für LCA5 Antikörper (N-Term) (ABIN2785382)

Target: LCA5 (Leber Congenital Amaurosis 5 (LCA5))

Reaktivität: Human, Maus, Ratte, Hund, Meerschweinchen, Pferd, Kaninchen, Rind (Kuh)

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser LCA5 Antikörper ist unkonjugiert

Applikation: Western Blotting (WB)

Produktdetails anti-LCA5 Antikörper

Bindungsspezifität: N-Term

Verwendungszweck: LCA5 Antibody - N-terminal region

Sequenz: FSLQKLKEIS EARHLPERDD LAKKLVSAEL KLDDTERRIK ELSKNLELST

Homologie: Cow: 92%, Dog: 100%, Guinea Pig: 100%, Horse: 100%, Human: 100%, Mouse: 93%, Rabbit: 100%, Rat: 100%

Produktmerkmale: This is a rabbit polyclonal antibody against LCA5. It was validated on Western Blot using a cell lysate as a positive control.

Aufreinigung: Affinity Purified

Immunogen: The immunogen is a synthetic peptide directed towards the N terminal region of human LCA5

Anwendungsinformationen

Applikationshinweise: Optimal working dilution should be determined by the investigator.

Kommentare:

We also sell a specific blocking peptide that can be used in combination with this antibody. You can find the blocking peptide under AAP53410-100UG

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Konzentration: 0.5 mg/mL

Buffer: Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handhabung: prevent freeze-thaw cycles

Lagerung: 4 °C,-20 °C

Informationen zur Lagerung: For short term use, store at 2-8C up to 1 week. For long term storage, store at -20 °C in small aliquots to prevent freeze-thaw cycles.

Referenzen für anti-LCA5 Antikörper (ABIN2785382)

Ramprasad, Soumittra, Nancarrow, Sen, McKibbin, Williams, Arokiasamy, Lakshmipathy, Inglehearn, Kumaramanickavel: "Identification of a novel splice-site mutation in the Lebercilin (LCA5) gene causing Leber congenital amaurosis." in: Molecular vision, Vol. 14, pp. 481-6, (2008) (PubMed).

Details zu LCA5

Target: LCA5 (Leber Congenital Amaurosis 5 (LCA5))

Andere Bezeichnung: LCA5

Hintergrund:

Background Information: LCA5 is a protein that is thought to be involved in centrosomal or ciliary functions. Mutations in this gene cause Leber congenital amaurosis type V. This gene encodes a protein that is thought to be involved in centrosomal or ciliary functions. Mutations in this gene cause Leber congenital amaurosis type V. Alternative splicing results in two transcript variants.

Gene Name: Leber congenital amaurosis 5

Alternative Symbols: C6orf152

Protein Name: Lebercilin

Molekulargewicht: 80kDa

Gen-ID: 167691

NCBI Accession: NP_859065

UniProt: Q86VQ0