LCA5 Antikörper (Leber Congenital Amaurosis 5) (N-Term)

Details for Product anti-LCA5 Antibody No. ABIN2785382, Anbieter: Anmelden zum Anzeigen
Antigen
  • C6orf152
  • RGD1308555
  • 4930431B11Rik
  • 5730406O13Rik
  • AV274874
  • ORF64
  • LCA5, lebercilin
  • Leber congenital amaurosis 5
  • Leber congenital amaurosis 5 (human)
  • LCA5
  • LOC787523
  • Lca5
Epitop
N-Term
4
2
2
1
Reaktivität
Rind (Kuh), Hund, Meerschweinchen, Pferd, Human, Maus, Kaninchen, Ratte (Rattus)
32
17
17
1
1
1
1
1
1
Wirt
Kaninchen
32
Klonalität
Polyklonal
Konjugat
Dieser LCA5 Antikörper ist unkonjugiert
2
2
2
1
1
1
1
1
1
1
1
1
1
1
Applikation
Western Blotting (WB)
16
13
11
6
5
Optionen
Hersteller
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Hersteller Produkt- Nr.
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Immunogen The immunogen is a synthetic peptide directed towards the N terminal region of human LCA5
Blocking Peptide Zu diesem Produkt passt das Blocking Peptide ABIN979227.
Sequenz FSLQKLKEIS EARHLPERDD LAKKLVSAEL KLDDTERRIK ELSKNLELST
Homologie Cow: 92%, Dog: 100%, Guinea Pig: 100%, Horse: 100%, Human: 100%, Mouse: 93%, Rabbit: 100%, Rat: 100%
Produktmerkmale This is a rabbit polyclonal antibody against LCA5. It was validated on Western Blot using a cell lysate as a positive control.
Reinigung Affinity Purified
Plasmids, Primers & others Plasmide, Primers & weitere LCA5 products on genomics-online (e.g. as negative or positive controls)
Antigen
Andere Bezeichnung LCA5 (LCA5 Antibody Abstract)
Hintergrund LCA5 is a protein that is thought to be involved in centrosomal or ciliary functions. Mutations in this gene cause Leber congenital amaurosis type V. This gene encodes a protein that is thought to be involved in centrosomal or ciliary functions. Mutations in this gene cause Leber congenital amaurosis type V. Alternative splicing results in two transcript variants.
Alias Symbols: C6orf152
Protein Interaction Partner: TXLNA, RCOR3, SRPK2,
Protein Size: 697
Molekulargewicht 80 kDa
Gen-ID 167691
NCBI Accession NM_181714, NP_859065
UniProt Q86VQ0
Applikations-hinweise Optimal working dilutions should be determined experimentally by the investigator.
Kommentare

Antigen size: 697 AA

Beschränkungen Nur für Forschungszwecke einsetzbar
Format Liquid
Konzentration Lot specific
Buffer Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.
Konservierungs-mittel Sodium azide
Vorsichtsmaßnahmen This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
Handhabung Avoid repeated freeze-thaw cycles.
Lagerung -20 °C
Informationen zur Lagerung For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.
Bilder des Herstellers
Western Blotting (WB) image for anti-Leber Congenital Amaurosis 5 (LCA5) (N-Term) antibody (ABIN2785382) WB Suggested Anti-LCA5 Antibody Titration: 0.2-1 ug/ml
Positive Control:...
Produkt verwendet in: Ramprasad, Soumittra, Nancarrow, Sen, McKibbin, Williams, Arokiasamy, Lakshmipathy, Inglehearn, Kumaramanickavel: "Identification of a novel splice-site mutation in the Lebercilin (LCA5) gene causing Leber congenital amaurosis." in: Molecular vision, Vol. 14, pp. 481-6, 2008 (PubMed).

Allgemeine Veröffentlichungen Hitani, Yokoo, Honda, Usui, Yamagami, Amano: "Transplantation of a sheet of human corneal endothelial cell in a rabbit model." in: Molecular vision, Vol. 14, pp. 1-9, 2008 (PubMed).

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