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LCA5 Antikörper (N-Term)

Dieses Kaninchen Polyklonal-Antikörper erkennt spezifisch LCA5 in WB. Er zeigt eine Reaktivität gegenüber Human, Maus, Ratte, Hund, Meerschweinchen, Pferd, Kaninchen und Rind (Kuh) und wurde in 1 Publikation erwähnt.
Produktnummer ABIN2785382

Kurzübersicht für LCA5 Antikörper (N-Term) (ABIN2785382)

Target

Alle LCA5 Antikörper anzeigen
LCA5 (Leber Congenital Amaurosis 5 (LCA5))

Reaktivität

  • 26
  • 17
  • 16
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
Human, Maus, Ratte, Hund, Meerschweinchen, Pferd, Kaninchen, Rind (Kuh)

Wirt

  • 26
Kaninchen

Klonalität

  • 26
Polyklonal

Konjugat

  • 8
  • 3
  • 2
  • 2
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
Dieser LCA5 Antikörper ist unkonjugiert

Applikation

  • 22
  • 13
  • 7
  • 3
  • 2
Western Blotting (WB)
  • Bindungsspezifität

    • 7
    • 1
    • 1
    • 1
    • 1
    N-Term

    Sequenz

    FSLQKLKEIS EARHLPERDD LAKKLVSAEL KLDDTERRIK ELSKNLELST

    Homologie

    Cow: 92%, Dog: 100%, Guinea Pig: 100%, Horse: 100%, Human: 100%, Mouse: 93%, Rabbit: 100%, Rat: 100%

    Produktmerkmale

    This is a rabbit polyclonal antibody against LCA5. It was validated on Western Blot using a cell lysate as a positive control.

    Aufreinigung

    Affinity Purified

    Immunogen

    The immunogen is a synthetic peptide directed towards the N terminal region of human LCA5
  • Applikationshinweise

    Optimal working dilutions should be determined experimentally by the investigator.

    Kommentare

    Antigen size: 697 AA

    Beschränkungen

    Nur für Forschungszwecke einsetzbar
  • Format

    Liquid

    Konzentration

    Lot specific

    Buffer

    Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.

    Konservierungsmittel

    Sodium azide

    Vorsichtsmaßnahmen

    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

    Handhabung

    Avoid repeated freeze-thaw cycles.

    Lagerung

    -20 °C

    Informationen zur Lagerung

    For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.
  • Ramprasad, Soumittra, Nancarrow, Sen, McKibbin, Williams, Arokiasamy, Lakshmipathy, Inglehearn, Kumaramanickavel: "Identification of a novel splice-site mutation in the Lebercilin (LCA5) gene causing Leber congenital amaurosis." in: Molecular vision, Vol. 14, pp. 481-6, (2008) (PubMed).

  • Target

    LCA5 (Leber Congenital Amaurosis 5 (LCA5))

    Andere Bezeichnung

    LCA5

    Hintergrund

    LCA5 is a protein that is thought to be involved in centrosomal or ciliary functions. Mutations in this gene cause Leber congenital amaurosis type V. This gene encodes a protein that is thought to be involved in centrosomal or ciliary functions. Mutations in this gene cause Leber congenital amaurosis type V. Alternative splicing results in two transcript variants.
    Alias Symbols: C6orf152
    Protein Interaction Partner: TXLNA, RCOR3, SRPK2,
    Protein Size: 697

    Molekulargewicht

    80 kDa

    Gen-ID

    167691

    NCBI Accession

    NM_181714, NP_859065

    UniProt

    Q86VQ0
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