CCDC50 Antikörper (Middle Region)

Produktnummer ABIN311564

Produktdetails anti-CCDC50 Antikörper

Target: CCDC50 (Coiled-Coil Domain Containing 50 (CCDC50))

Bindungsspezifität: Middle Region

Reaktivität: Human, Maus, Ratte, Kaninchen, Pferd, Rind (Kuh), Hund, Meerschweinchen, Zebrafisch (Danio rerio)

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser CCDC50 Antikörper ist unkonjugiert

Applikation: Western Blotting (WB)

Sequenz: GMKPRVMKEA VSTPSRMAHR DQEWYDAEIA RKLQEEELLA TQVDMRAAQV

Homologie: Cow: 100%, Dog: 100%, Guinea Pig: 100%, Horse: 100%, Human: 100%, Mouse: 100%, Rabbit: 100%, Rat: 100%, Zebrafish: 77%

Produktmerkmale: This is a rabbit polyclonal antibody against CCDC50. It was validated on Western Blot using a cell lysate as a positive control.

Aufreinigung: Affinity Purified

Immunogen: The immunogen is a synthetic peptide directed towards the middle region of human CCDC50

Anwendungsinformationen

Applikationshinweise: Optimal working dilutions should be determined experimentally by the investigator.

Kommentare:

Antigen size: 482 AA

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Konzentration: Lot specific

Buffer: Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handhabung: Avoid repeated freeze-thaw cycles.

Lagerung: -20 °C

Informationen zur Lagerung: For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.

Details zu CCDC50

Target: CCDC50 (Coiled-Coil Domain Containing 50 (CCDC50))

Andere Bezeichnung: CCDC50 (CCDC50 Produkte)

Hintergrund: CCDC50 is a soluble, cytoplasmic, tyrosine-phosphorylated protein with multiple ubiquitin-interacting domains. Mutations in this gene cause nonsyndromic, postlingual, progressive sensorineural DFNA44 hearing loss. In mouse, the protein is expressed in the inner ear during development and postnatal maturation and associates with microtubule-based structures. This protein may also function as a negative regulator of NF-kB signaling and as an effector of epidermal growth factor (EGF)-mediated cell signaling.
Alias Symbols: C3orf6, DFNA44, YMER
Protein Interaction Partner: UBC, SH3RF2, RIPK1, TNFAIP3, EGFR, RPS3A,
Protein Size: 482

Molekulargewicht: 56 kDa

Gen-ID: 152137

NCBI Accession: NM_178335, NP_848018

UniProt: Q8IVM0