TTL Antikörper (Middle Region)

Produktnummer ABIN2785284

Der Kaninchen Polyklonal anti-TTL Antikörper wird verwendet zum Nachweis von TTL in Proben von Human, Maus, Ratte, Rind (Kuh), Hund, Meerschweinchen, Pferd, Kaninchen und Zebrafisch (Danio rerio). Er wurde validiert für WB.

Kurzübersicht für TTL Antikörper (Middle Region) (ABIN2785284)

Target: TTL (Tubulin tyrosine Ligase (TTL))

Reaktivität: Human, Maus, Ratte, Rind (Kuh), Hund, Meerschweinchen, Pferd, Kaninchen, Zebrafisch (Danio rerio)

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser TTL Antikörper ist unkonjugiert

Applikation: Western Blotting (WB)

Produktdetails anti-TTL Antikörper

Bindungsspezifität: Middle Region

Verwendungszweck: TTL Antibody - middle region

Sequenz: LYREGVLRTA SEPYHVDNFQ DKTCHLTNHC IQKEYSKNYG KYEEGNEMFF

Homologie: Cow: 100%, Dog: 100%, Guinea Pig: 100%, Horse: 100%, Human: 100%, Mouse: 100%, Rabbit: 100%, Rat: 100%, Zebrafish: 79%

Produktmerkmale: This is a rabbit polyclonal antibody against TTL. It was validated on Western Blot using a cell lysate as a positive control.

Aufreinigung: Affinity Purified

Immunogen: The immunogen is a synthetic peptide directed towards the middle region of human TTL

Anwendungsinformationen

Applikationshinweise: Optimal working dilution should be determined by the investigator.

Kommentare:

We also sell a specific blocking peptide that can be used in combination with this antibody. You can find the blocking peptide under AAP53199-100UG

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Konzentration: 0.5 mg/mL

Buffer: Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handhabung: prevent freeze-thaw cycles

Lagerung: 4 °C,-20 °C

Informationen zur Lagerung: For short term use, store at 2-8C up to 1 week. For long term storage, store at -20 °C in small aliquots to prevent freeze-thaw cycles.

Details zu TTL

Target: TTL (Tubulin tyrosine Ligase (TTL))

Andere Bezeichnung: TTL

Hintergrund:

Background Information: TTL catalyzes the post-translational addition of a tyrosine to the C-terminal end of detyrosinated alpha-tubulin.TTL is a cytosolic enzyme involved in the posttranslational modification of alpha-tubulin (see MIM 602529). Alpha-tubulin within assembled microtubules is detyrosinated over time at the C terminus. After microtubule disassembly, TTL restores the tyrosine residues and consequently participates in a cycle of tubulin detyrosination and tyrosination (Erck et al., 2003 [PubMed 14571137]).[supplied by OMIM].

Gene Name: Tubulin tyrosine ligase

Alternative Symbols: MGC46235

Protein Name: Tubulin--tyrosine ligase

Molekulargewicht: 43kDa

Gen-ID: 150465

NCBI Accession: NP_714923

UniProt: Q8NG68

Pathways: Regulation of Cell Size