RDH12 Antikörper (Middle Region)

Produktnummer ABIN2785176

Der Kaninchen Polyklonal Anti-RDH12-Antikörper wurde für WB validiert. Er ist geeignet, RDH12 in Proben von Human, Schwein, Ratte, Hund, Rind (Kuh), Meerschweinchen, Kaninchen, Pferd, Saccharomyces cerevisiae und Zebrafisch (Danio rerio) zu detektieren.

Kurzübersicht für RDH12 Antikörper (Middle Region) (ABIN2785176)

Target: RDH12 (Retinol Dehydrogenase 12 (All-Trans/9-Cis/11-Cis) (RDH12))

Reaktivität: Human, Schwein, Ratte, Hund, Rind (Kuh), Meerschweinchen, Kaninchen, Pferd, Saccharomyces cerevisiae, Zebrafisch (Danio rerio)

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser RDH12 Antikörper ist unkonjugiert

Applikation: Western Blotting (WB)

Produktdetails anti-RDH12 Antikörper

Bindungsspezifität: Middle Region

Sequenz: AKRLQGTGVT TYAVHPGVVR SELVRHSSLL CLLWRLFSPF VKTAREGAQT

Homologie: Cow: 85%, Dog: 92%, Guinea Pig: 79%, Horse: 86%, Human: 100%, Pig: 86%, Rabbit: 85%, Rat: 79%, Yeast: 79%, Zebrafish: 92%

Produktmerkmale: This is a rabbit polyclonal antibody against RDH12. It was validated on Western Blot using a cell lysate as a positive control.

Aufreinigung: Affinity Purified

Immunogen: The immunogen is a synthetic peptide directed towards the middle region of human RDH12

Anwendungsinformationen

Applikationshinweise: Optimal working dilutions should be determined experimentally by the investigator.

Kommentare:

Antigen size: 316 AA

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Konzentration: Lot specific

Buffer: Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handhabung: Avoid repeated freeze-thaw cycles.

Lagerung: -20 °C

Informationen zur Lagerung: For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.

Details zu RDH12

Target: RDH12 (Retinol Dehydrogenase 12 (All-Trans/9-Cis/11-Cis) (RDH12))

Andere Bezeichnung: RDH12

Hintergrund: RDH12 is an NADPH-dependent retinal reductase whose highest activity is toward 9-cis and all-trans-retinol. RDH12 also plays a role in the metabolism of short-chain aldehydes but does not exhibit steroid dehydrogenase activity. Defects in this gene are a cause of Leber congenital amaurosis type 3 (LCA3). The protein encoded by this gene is an NADPH-dependent retinal reductase whose highest activity is toward 9-cis and all-trans-retinol. The encoded enzyme also plays a role in the metabolism of short-chain aldehydes but does not exhibit steroid dehydrogenase activity. Defects in this gene are a cause of Leber congenital amaurosis type 3 (LCA3).
Alias Symbols: FLJ30273, LCA3, LCA13, SDR7C2
Protein Interaction Partner: RBPMS, UBC, ANXA8L1, MAP1LC3A, BUB1,
Protein Size: 316

Molekulargewicht: 35 kDa

Gen-ID: 145226

NCBI Accession: NM_152443, NP_689656

UniProt: Q96NR8